Significance of Visual Evoked Potentials in the Assessment of Visual Field Defects in Primary Open-Angle Glaucoma: A Review.

Neuroscience journal Pub Date : 2013-01-01 Epub Date: 2012-12-06 DOI:10.1155/2013/418320
Ruchi Kothari, Pradeep Bokariya, Smita Singh, Ramji Singh
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引用次数: 13

Abstract

Visual evoked potentials is an important visual electrophysiological tool which has been used for the evaluation of visual field defects in primary open-angle glaucoma and is an appropriate objective measure of optic nerve function. Significant correlations between the magnitude of the VEP parameters and MD of Humphrey static perimetry suggest that the impaired visual cortical responses observed in glaucoma patients can be revealed by both electrophysiological and psychophysical methods. In addition, the severity of global glaucomatous damage evidenced by reduction in MD could depend on the delay in neural conduction from retina to the visual cortex as revealed by the significant correlation between VEP latencies and MD which also supports the validity of the VEP testing in progression of glaucoma.

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视觉诱发电位在原发性开角型青光眼视野缺损评价中的意义
视觉诱发电位是评价原发性开角型青光眼视野缺损的一种重要的视觉电生理工具,是评价视神经功能的一种合适的客观指标。汉弗莱静态视野检查VEP参数的大小与MD之间存在显著相关性,提示青光眼患者的视皮层反应受损可以通过电生理和心理物理两种方法来揭示。此外,VEP潜伏期与MD之间的显著相关性也揭示了VEP检测在青光眼进展中的有效性,由此可见,MD降低所证明的青光眼损伤的严重程度可能与视网膜到视觉皮层的神经传导延迟有关。
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