Effect of Cinnamon Extract and Chlorhexidine Gluconate (0.2%) on the Clinical Level of Dental Plaque and Gingival Health: A 4-Week, Triple-Blind Randomized Controlled Trial.

Devanand Gupta, Ankita Jain
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Abstract

Aim: To compare the effect of cinnamon extract, chlorhexidine mouthwash and placebo on dental plaque level and gingivitis.

Materials and methods: One hundred five healthy dental and medical students aged 21 to 25 years participated in the study. The subjects were randomly divided into three groups: i.e., the cinnamon group, the chlorhexidine gluconate mouthwash group and the placebo (distilled water) group. Data were collected at baseline, the 15th and the 30th day. Plaque was disclosed using erythrosine disclosing agent and scores were recorded using the Quigley and Hein plaque index modified by Turesky-Gilmore-Glickman. Gingival scoring was done by the gingival index of Löe and Silness. Statistical analysis was carried out to compare the effect of all three treatments groups; p ≤ 0.05 was considered statistically significant.

Results: The chlorhexidine group showed the maximum decrease in both plaque and gingival scores, followed by cinnamon extract, but the result was statistically insignificant. The plaque and gingival scores remained almost unchanged in the distilled water group. Conclusion: The results of the present study indicate that cinnamon may prove to be an effective agent owing to its ability to reduce plaque level and gingivitis.

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肉桂提取物和葡萄糖酸氯己定(0.2%)对牙菌斑临床水平和牙龈健康的影响:一项为期4周的三盲随机对照试验
目的:比较肉桂提取物、氯己定漱口水和安慰剂对牙菌斑水平和牙龈炎的影响。材料与方法:105名年龄在21 ~ 25岁之间的健康牙科和医学学生参与了研究。受试者被随机分为三组:肉桂组、葡萄糖酸氯己定漱口水组和安慰剂(蒸馏水)组。在基线、第15天和第30天收集数据。使用红血素揭露剂揭露斑块,使用Turesky-Gilmore-Glickman修正的Quigley和Hein斑块指数记录评分。采用牙龈指数Löe和Silness进行牙龈评分。对三个治疗组的疗效进行统计学分析比较;P≤0.05认为有统计学意义。结果:氯己定组菌斑和牙龈评分下降幅度最大,肉桂提取物组次之,但差异无统计学意义。蒸馏水组的牙菌斑和牙龈评分几乎没有变化。结论:本研究结果表明,肉桂可能被证明是一种有效的药物,因为它能够减少菌斑水平和牙龈炎。
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