下载PDF
{"title":"LipidXplorer: Software for Quantitative Shotgun Lipidomics Compatible with Multiple Mass Spectrometry Platforms","authors":"Ronny Herzog, Dominik Schwudke, Andrej Shevchenko","doi":"10.1002/0471250953.bi1412s43","DOIUrl":null,"url":null,"abstract":"<p>LipidXplorer is an open-source software kit that supports the identification and quantification of molecular species of any lipid class detected by shotgun experiments performed on any mass spectrometry platform. LipidXplorer does not rely on a database of reference spectra: instead, lipid identification routines are user defined in the declarative molecular fragmentation query language (MFQL). The software supports batch processing of multiple shotgun acquisitions by high-resolution mass mapping, precursor and neutral-loss scanning, and data-dependent MS/MS lending itself to a variety of lipidomics applications in cell biology and molecular medicine. <i>Curr. Protoc. Bioinform</i>. 43:14.12.1-14.12.30. © 2013 by John Wiley & Sons, Inc.</p>","PeriodicalId":10958,"journal":{"name":"Current protocols in bioinformatics","volume":"43 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/0471250953.bi1412s43","citationCount":"49","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current protocols in bioinformatics","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/0471250953.bi1412s43","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 49
引用
批量引用
Abstract
LipidXplorer is an open-source software kit that supports the identification and quantification of molecular species of any lipid class detected by shotgun experiments performed on any mass spectrometry platform. LipidXplorer does not rely on a database of reference spectra: instead, lipid identification routines are user defined in the declarative molecular fragmentation query language (MFQL). The software supports batch processing of multiple shotgun acquisitions by high-resolution mass mapping, precursor and neutral-loss scanning, and data-dependent MS/MS lending itself to a variety of lipidomics applications in cell biology and molecular medicine. Curr. Protoc. Bioinform . 43:14.12.1-14.12.30. © 2013 by John Wiley & Sons, Inc.
LipidXplorer:与多个质谱平台兼容的定量霰弹枪脂组学软件
LipidXplorer是一款开源软件，支持在任何质谱平台上通过霰弹枪实验检测到的任何脂类分子种类的鉴定和定量。LipidXplorer不依赖于参考光谱数据库:相反，脂质鉴定例程是用户在声明性分子碎片查询语言(MFQL)中定义的。该软件通过高分辨率质量图谱、前体和中性损失扫描，以及数据依赖的质谱联用技术，支持批量处理多个霰弹枪采集的数据，这些数据可用于细胞生物学和分子医学中的各种脂质组学应用。咕咕叫。Protoc。Bioinform 43:14.12.1-14.12.30。©2013 by John Wiley &儿子,Inc。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
