Photoletter to the editor: Topical 0.5% brimonidine gel to camouflage redness of immature scars.

Markus Reinholz, Markus Heppt, Julia K Tietze, Thomas Ruzicka, Gerd G Gauglitz, Jürgen Schauber
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引用次数: 3

Abstract

Cutaneous scars develop as a result of a defective wound healing process. Scars are commonly visible as erythematous, sometimes disfiguring lesions which might be stigmatizing for the affected patient. Only a few therapies to improve the appearance of scars are available. Recently, brimonidine - a selective α2-receptor-agonist which causes vasoconstriction of small cutaneous vessels - was approved for the treatment of erythemato-telangiectatic rosacea. Topical brimonidine might also be helpful to improve redness of immature scars. Here we report on the effect of brimonidine 0.5% gel on a flat, erythematous scar in a 25-year-old female patient. Whitening of the scar could be observed immediately after application of brimonidine 0.5% gel and a good clinical result was observed within one hour. This effect lasted for up to three hours. We conclude that brimonidine 0.5% gel is a suitable topical therapy to reduce erythema in visible cutaneous scars.

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给编辑的信:外用0.5%溴胺凝胶来掩盖未成熟疤痕的红肿。
皮肤疤痕是由于伤口愈合过程的缺陷而产生的。疤痕通常是可见的红斑,有时毁容的病变,这可能是受影响的病人的耻辱。只有几种治疗方法可以改善疤痕的外观。最近,溴莫尼定-一种选择性α2受体激动剂,可引起小皮肤血管收缩-被批准用于治疗红斑毛细血管扩张型酒痤疮。局部使用溴硝定也可能有助于改善未成熟疤痕的发红。在这里,我们报告0.5%溴莫尼定凝胶对25岁女性患者扁平红斑疤痕的影响。0.5%溴莫尼定凝胶敷后即刻可观察到瘢痕的增白,1小时内临床效果良好。这种效果持续了三个小时。我们认为0.5%溴莫尼定凝胶是一种合适的局部治疗方法,可以减少可见皮肤疤痕的红斑。
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