Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology.

Q3 Biochemistry, Genetics and Molecular Biology International Journal of Cell Biology Pub Date : 2015-01-01 Epub Date: 2015-09-10 DOI:10.1155/2015/563818
Jaime M Cyphert, Carol S Trempus, Stavros Garantziotis
{"title":"Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology.","authors":"Jaime M Cyphert,&nbsp;Carol S Trempus,&nbsp;Stavros Garantziotis","doi":"10.1155/2015/563818","DOIUrl":null,"url":null,"abstract":"<p><p>Hyaluronan signaling properties are unique among other biologically active molecules, that they are apparently not influenced by postsynthetic molecular modification, but by hyaluronan fragment size. This review summarizes the current knowledge about the generation of hyaluronan fragments of different size and size-dependent differences in hyaluronan signaling as well as their downstream biological effects. </p>","PeriodicalId":39084,"journal":{"name":"International Journal of Cell Biology","volume":"2015 ","pages":"563818"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/563818","citationCount":"279","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Cell Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2015/563818","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/9/10 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 279

Abstract

Hyaluronan signaling properties are unique among other biologically active molecules, that they are apparently not influenced by postsynthetic molecular modification, but by hyaluronan fragment size. This review summarizes the current knowledge about the generation of hyaluronan fragments of different size and size-dependent differences in hyaluronan signaling as well as their downstream biological effects.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
大小问题:细胞生物学中透明质酸作用的分子量特异性。
透明质酸的信号特性在其他生物活性分子中是独一无二的,它们显然不受合成后分子修饰的影响,而是受透明质酸片段大小的影响。本文综述了目前关于不同大小的透明质酸片段的产生、透明质酸信号的大小依赖性差异及其下游生物学效应的研究进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
International Journal of Cell Biology
International Journal of Cell Biology Biochemistry, Genetics and Molecular Biology-Cell Biology
CiteScore
3.30
自引率
0.00%
发文量
4
审稿时长
20 weeks
期刊最新文献
A Comparative Study on the Effects of Mesenchymal Stem Cells and Their Conditioned Medium on Caco-2 Cells as an In Vitro Model for Inflammatory Bowel Disease. The Effect of Exposure to Mobile Phones on Electrical Cardiac Measurements: A Multivariate Analysis and a Variable Selection Algorithm to Detect the Relationship With Mean Changes. The Role of Bcl-2 Family Proteins and Sorafenib Resistance in Hepatocellular Carcinoma. Mitotic Kinases Aurora-A, Plk1, and Cdk1 Interact with Elk-1 Transcription Factor through the N-Terminal Domain. Acute Genetic Damage Induced by Ethanol and Corticosterone Seems to Modulate Hippocampal Astrocyte Signaling.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1