Exogenous lipid pneumonia related to long-term use of Vicks VapoRub® by an adult patient: a case report.

Q2 Medicine BMC Ear, Nose and Throat Disorders Pub Date : 2016-08-19 eCollection Date: 2016-01-01 DOI:10.1186/s12901-016-0032-6
I Cherrez Ojeda, J C Calderon, J Guevara, D Cabrera, E Calero, A Cherrez
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引用次数: 6

Abstract

Background: Use of petroleum-based over the counter remedies such as Vicks VapoRub to alleviate symptoms of rhinitis is common and can be effective, but carries under-appreciated risks of adverse side effects. In this case report we highlight Exogenous Lipoid Pneumonia (ELP), an uncommon condition that results from accumulation of exogenous lipids in the alveoli, as an adverse side effect of long-term Vicks VapoRub use.

Case presentation: We present the case of an 85-year-old female patient with ELP apparently due to continuous application of Vicks VapoRub® to her nostrils to alleviate chronic rhinitis. She was diagnosed incidentally via chest radiograph and computed tomography (CT) scan done as follow up to finding elevated C-reactive Protein during a routine exam. The CT scan revealed a pulmonary consolidation in the lower lobe of the right lung with fat density combined with low density areas associated with focal ground-glass opacities. The patient was advised to discontinue use of petroleum-based products, and was prescribed intranasal corticosteroids for her rhinitis. Follow up 2 years later showed that the lipid consolidation had diminished in size by approximately 10 %.

Conclusion: Physicians must be aware that ELP can develop as a result of long-term application of petroleum-based oils and ointments to the nose and discourage such use of these products. Patients who have used petroleum-based products in this way should be screened for ELP. CT scan is the best imaging modality for establishing the diagnosis. The treatment of this condition is not well defined, but, as shown in this case, the size of the lipid mass can decrease after use of petroleum based substances is discontinued.

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外源性脂质肺炎与长期使用维克斯®的成人患者:一个病例报告。
背景:使用以石油为基础的非处方疗法,如维克斯药膏,来缓解鼻炎的症状是常见的,而且是有效的,但却有被低估的副作用风险。在本病例报告中,我们强调外源性脂质肺炎(ELP),这是一种罕见的疾病,由外源性脂质在肺泡积聚引起,是长期使用维克斯药膏的不良副作用。病例介绍:我们报告了一例85岁的女性ELP患者,显然是由于持续应用维克斯蒸发膏®在她的鼻孔缓解慢性鼻炎。在常规检查中发现c反应蛋白升高,通过胸部x线片和计算机断层扫描(CT)偶然诊断。CT示右肺下叶肺实变,伴脂肪密度及低密度区伴局灶性磨玻璃影。建议患者停止使用石油产品,并为她的鼻炎开了鼻内皮质类固醇。2年后的随访显示,脂质实变缩小了约10%。结论:医生必须意识到ELP可能是长期使用石油基油和软膏的结果,并劝阻使用这些产品。以这种方式使用过石油基产品的患者应进行ELP筛查。CT扫描是确定诊断的最佳成像方式。这种情况的治疗还没有很好的定义,但是,正如本例所示,停止使用石油基物质后,脂质团块的大小可以减少。
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来源期刊
BMC Ear, Nose and Throat Disorders
BMC Ear, Nose and Throat Disorders Medicine-Otorhinolaryngology
CiteScore
3.30
自引率
0.00%
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0
期刊介绍: BMC Ear, Nose and Throat Disorders is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of ear, nose and throat disorders, as well as related molecular genetics, pathophysiology, and epidemiology. BMC Ear, Nose and Throat Disorders (ISSN 1472-6815) is indexed/tracked/covered by PubMed, CAS, EMBASE, Scopus and Google Scholar.
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