Use of the gamma probe to identify multigland disease in primary hyperparathyroidism.

Kirby Tobin, Rachel R Ayers, Mohammad Rajaei, Rebecca S Sippel, Courtney J Balentine, Dawn Elfenbein, Herb Chen, David F Schneider
{"title":"Use of the gamma probe to identify multigland disease in primary hyperparathyroidism.","authors":"Kirby Tobin,&nbsp;Rachel R Ayers,&nbsp;Mohammad Rajaei,&nbsp;Rebecca S Sippel,&nbsp;Courtney J Balentine,&nbsp;Dawn Elfenbein,&nbsp;Herb Chen,&nbsp;David F Schneider","doi":"10.2217/ije.15.27","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>The purpose of this study was to determine threshold gamma probe counts to distinguish single adenoma (SA) from multigland disease (MGD) during radioguided parathyroidectomy.</p><p><strong>Methods: </strong>A retrospective analysis of 1656 patients was performed. <i>Ex vivo</i> counts of the first excised gland were taken and recorded as a percentage of background counts.</p><p><strong>Results: </strong>69.4% of MGD patients had counts below the 50% threshold. The 50% threshold correctly grouped 72.8% of our cohort. Counts of more than 100% were accurate for grouping SA, with only 6.8% of patients with counts more than 100% having MGD.</p><p><strong>Conclusions: </strong>The gamma probe can aid surgeons in deciding to continue neck exploration if MGD is suspected or wait for labs to confirm cure if SA is suspected.</p>","PeriodicalId":42691,"journal":{"name":"International Journal of Endocrine Oncology","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/ije.15.27","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Endocrine Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/ije.15.27","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5

Abstract

Aim: The purpose of this study was to determine threshold gamma probe counts to distinguish single adenoma (SA) from multigland disease (MGD) during radioguided parathyroidectomy.

Methods: A retrospective analysis of 1656 patients was performed. Ex vivo counts of the first excised gland were taken and recorded as a percentage of background counts.

Results: 69.4% of MGD patients had counts below the 50% threshold. The 50% threshold correctly grouped 72.8% of our cohort. Counts of more than 100% were accurate for grouping SA, with only 6.8% of patients with counts more than 100% having MGD.

Conclusions: The gamma probe can aid surgeons in deciding to continue neck exploration if MGD is suspected or wait for labs to confirm cure if SA is suspected.

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
使用伽玛探针识别原发性甲状旁腺功能亢进的多腺体疾病。
目的:本研究的目的是在放射引导下甲状旁腺切除术中确定阈值伽马探针计数以区分单一腺瘤(SA)和多腺疾病(MGD)。方法:对1656例患者进行回顾性分析。取第一个切除腺体的离体计数并记录为背景计数的百分比。结果:69.4%的MGD患者计数低于50%阈值。50%的阈值正确分组了72.8%的队列。计数超过100%对SA的分类是准确的,计数超过100%的患者中只有6.8%患有MGD。结论:伽玛探头可以帮助外科医生在怀疑MGD时决定继续颈部探查,或在怀疑SA时等待实验室确认治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
审稿时长
13 weeks
期刊介绍: International Journal of Endocrine Oncology is a quarterly, peer-reviewed journal that helps the clinician to keep up to date with best practice in this fast-moving field. The journal highlights significant advances in basic and translational research, and places them in context for future therapy. The journal presents the latest research findings in diagnosis and management of endocrine cancer, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. The journal welcomes the unsolicited submission of article proposals and original research manuscripts.
期刊最新文献
Neoadjuvant use of lenvatinib in locally advanced papillary thyroid carcinoma involving critical vessels Recurrence-free survival following aggressive multimodal treatment of an isolated recurrence of adrenocortical carcinoma French patient-reported experience of diagnosis, management and burden of neuroendocrine tumors Bad kits in the diagnosis of endocrine tumors Somatotroph adenomas: histological subtypes and predicted response to treatment
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1