Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT.

Uttam Shrestha, Elias H Botvinick, Yerem Yeghiazarians, Youngho Seo, Grant T Gullberg
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引用次数: 1

Abstract

Coronary steal (CS) is a physiological process that induces absolute decrease in blood flow in collateralized myocardium compared to resting flow during coronary vasodilation due to redistribution of blood away from collateral-dependent myocardium. Although, CS has been well known for decades, there are very few noninvasive perfusion studies in humans that quantitatively predict the existence of CS. In this study, we show that the quantitative measurement of absolute value of regional myocardial blood flow (MBF) and coronary flow reserve (CFR) using dynamic single photon emitted computed tomography (SPECT) can help estimate the presence of CS in myocardium with obstructed coronary artery and collateral circulation.

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动态SPECT对侧支循环支持下冠状动脉闭塞患者冠状动脉偷窃的定量分析。
冠状动脉偷血(CS)是一种生理过程,在冠状动脉血管舒张过程中,由于血液从依赖侧支的心肌中重新分配,导致侧支心肌的血流量比静息血流量绝对减少。虽然CS已经被人们熟知了几十年,但很少有人类无创灌注研究能够定量预测CS的存在。在这项研究中,我们发现使用动态单光子发射计算机断层扫描(SPECT)定量测量区域心肌血流量(MBF)和冠状动脉血流储备(CFR)的绝对值可以帮助估计冠状动脉和侧枝循环阻塞的心肌中CS的存在。
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