Uttam Shrestha, Elias H Botvinick, Yerem Yeghiazarians, Youngho Seo, Grant T Gullberg
{"title":"Quantitative Signature of <i>Coronary Steal</i> in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT.","authors":"Uttam Shrestha, Elias H Botvinick, Yerem Yeghiazarians, Youngho Seo, Grant T Gullberg","doi":"10.1109/NSSMIC.2014.7430923","DOIUrl":null,"url":null,"abstract":"<p><p><i>Coronary steal</i> (CS) is a physiological process that induces absolute decrease in blood flow in collateralized myocardium compared to resting flow during coronary vasodilation due to redistribution of blood away from collateral-dependent myocardium. Although, CS has been well known for decades, there are very few noninvasive perfusion studies in humans that quantitatively predict the existence of CS. In this study, we show that the quantitative measurement of absolute value of regional myocardial blood flow (MBF) and coronary flow reserve (CFR) using dynamic single photon emitted computed tomography (SPECT) can help estimate the presence of CS in myocardium with obstructed coronary artery and collateral circulation.</p>","PeriodicalId":73298,"journal":{"name":"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium","volume":"2014 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/NSSMIC.2014.7430923","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NSSMIC.2014.7430923","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Coronary steal (CS) is a physiological process that induces absolute decrease in blood flow in collateralized myocardium compared to resting flow during coronary vasodilation due to redistribution of blood away from collateral-dependent myocardium. Although, CS has been well known for decades, there are very few noninvasive perfusion studies in humans that quantitatively predict the existence of CS. In this study, we show that the quantitative measurement of absolute value of regional myocardial blood flow (MBF) and coronary flow reserve (CFR) using dynamic single photon emitted computed tomography (SPECT) can help estimate the presence of CS in myocardium with obstructed coronary artery and collateral circulation.