[APPLICATION OF PREPARATION OF COCARNIT FOR PATIENTS AFTER ENDOPROSTHESIS OF HIP AND KNEE JOINTS].

Likars'ka sprava Pub Date : 2015-07-01
N A Korzh, V A Filippenko, F S Leont'eva, V A Tulyakov, S E Bondarenko
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Abstract

In the article the results of clinical researches of efficiency of preparation of Cocarnit are resulted for patients after endoprosthesis of large joints. It is routine that for patients, receiving preparation of Cocarnit after the operation period there was a decline in the amount of complaints of patients on the total somatical state. Preparation of Ccocarnit was positively estimated outside patients, meaningful by-reactions, serving reason of abolition of preparation, was not marked. At the reception preparation of Cocarnit greater part of investigational laboratory indexes (table of contents of glucose, β-lipoproteines, total chondroitisulfates, TBC-productes (malonic dyaldehyde), activity of aspartataminotransferase, alkaline phosphatase and β-glutamyltranspeptidase), the indexes of clinical blood test and leucocytar indexes during a supervision did not have reliable differences from such as the persons of the control group, that confirms good bearab leness of the indicated preparation. Application preparation of Cocarnit for patients in composition the chart of treatment of patients after endoprosthesis of large joints brought maintenance over of cholesterol to the decline, glycoproteins, TBC-products (malonic dyaldehyde), activity of alaninaminotransferase, that specifies on normalizing influence of the indicated preparation in relation to the basic types of exchange of matters.

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【cocarnit制剂在髋关节、膝关节置换术后患者中的应用】。
本文对大关节植入术后Cocarnit的制备效果进行了临床研究。对于患者来说,手术期后接受Cocarnit制剂,患者对总身体状态的投诉数量下降是常规的。患者外对柯柯尼的制备有积极评价,有意义的副反应,取消制备的服务原因,没有标记。在接受制剂时,大部分试验性实验室指标(葡萄糖、β-脂蛋白、总硫酸软骨素、tbc产物(丙二醛)、天冬氨酸转氨酶、碱性磷酸酶、β-谷氨酰转肽酶活性)、临床血检指标和监测期间白细胞指标与对照组等人无可靠差异。这证实了所述制剂的良好性能。Cocarnit在患者中的应用制剂构成了大关节内假体术后患者的治疗图表,使胆固醇维持在下降,糖蛋白,tbc产物(丙二醛),丙氨酸氨基转移酶活性,具体说明了所指示制剂对物质交换基本类型的正常化影响。
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