Cutaneous Metastasis as a First Presentation for Lung Adenocarcinoma.

Yazan Abdeen, Sawsan Amireh, Alpa Patel, Moh'd Al-Halawani, Hamid Shaaban, Richard Miller
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引用次数: 5

Abstract

Context: According to the recent World Health Organization reports, lung cancer has become the most common type of malignancy and the leading cause of death from cancer. Lung cancer frequently metastasizes to hilar lymphnodes, brain, adrenal glands, bone, but rarely to skin.

Case report: We report a case of a 72-year-old male with a past medical history of pulmonary fibrosis and no prior history of smoking who presented to the emergency room for progressive dyspnea over three weeks. The patient reported having a rapidly growing scalp lesion as well. A computed tomography (CT) scan of the chest showed diffuse fibrotic changes and multiple densities of different diameters; a CT guided biopsy of lung revealed a poorly differentiated adenocarcinoma. Excision of right scalp lesion was performed, and pathology revealed poorly differentiated malignant neoplasm favoring adenocarcinoma.

Conclusion: We are presenting a rare case of lung adenocarcinoma presenting with skin metastasis, which was simultaneously diagnosed during the same hospitalization. Although cutaneous metastasis from the lung is rare, it must be ruled out in patients with suspicious skin lesions, smoking history, or lung cancer.

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皮肤转移是肺腺癌的首要表现。
背景:根据世界卫生组织最近的报告,肺癌已成为最常见的恶性肿瘤类型,也是癌症死亡的主要原因。肺癌常转移到肺门淋巴结、脑、肾上腺、骨,但很少转移到皮肤。病例报告:我们报告一例72岁男性,既往有肺纤维化病史,既往无吸烟史,因进行性呼吸困难就诊超过三周。患者报告头皮病变也在迅速增长。胸部CT示弥漫性纤维化改变及不同直径的多发密度;CT引导下肺活检显示为低分化腺癌。右头皮病变切除,病理显示低分化恶性肿瘤倾向于腺癌。结论:我们报告一例罕见的肺腺癌合并皮肤转移的病例,该病例是在同一住院期间同时诊断的。虽然肺部皮肤转移是罕见的,但必须排除可疑的皮肤病变,吸烟史,或肺癌患者。
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