Prediction of oxygen uptake during walking in ambulatory persons with multiple sclerosis.

Stamatis Agiovlasitis, Brian M Sandroff, Robert W Motl
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引用次数: 8

Abstract

People with multiple sclerosis (MS) have an increased rate of gross oxygen uptake (gross-VO2) during treadmill walking, and their gross-VO2 may further vary with walking impairment. This study attempted to develop an equation for predicting gross-VO2 from walking speed and an index of walking impairment in persons with MS and examine its accuracy. Gross-VO2 was measured with open-circuit spirometry in 43 persons with MS (47 +/- 9 yr; 38 women) during five treadmill walking trials, each lasting 6 min, at 2.0, 2.5, 3.0, 3.5, and 4.0 mph (0.89, 1.12, 1.34, 1.56, and 1.79 m/s). The 12-Item Multiple Sclerosis Walking Scale (MSWS-12) and the single-item Patient Determined Disease Steps scale (PDDS) provided indices of walking impairment. Multilevel modeling with random intercepts and slopes showed significant effects of speed and MSWS-12 on gross-VO2 (p

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预测多发性硬化症患者行走时的摄氧量。
患有多发性硬化症(MS)的人在跑步机上行走时总摄氧量(总摄氧量)增加,并且他们的总摄氧量可能会随着行走障碍而进一步变化。本研究试图建立一个从步行速度和MS患者步行障碍指数预测总vo2的方程,并检验其准确性。用开路肺活量法测量43例MS患者的总摄氧量(47 +/- 9年;38名女性)进行了5次跑步机步行试验,每次持续6分钟,速度分别为2.0、2.5、3.0、3.5和4.0英里/小时(0.89、1.12、1.34、1.56和1.79米/秒)。12项多发性硬化症步行量表(MSWS-12)和单项患者确定疾病步数量表(PDDS)提供了步行障碍的指标。具有随机截距和斜率的多层模型显示,速度和MSWS-12对总vo2有显著影响(p
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