The evolving role of bariatric surgery in patients with type 1 diabetes and obesity.

Integrative obesity and diabetes Pub Date : 2016-01-01 Epub Date: 2016-02-15 DOI:10.15761/IOD.1000144
Ali A Rizvi
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Abstract

Bariatric surgery has emerged as a viable treatment option in morbidly obese individuals with type 2 diabetes. Concomitant with societal lifestyle changes and the increased emphasis on achieving metabolic targets, there has been a rise in the number of patients with type 1 diabetes (T1DM) who are overweight and obese. Preliminary experience based on a limited number of observational reports points to substantial weight loss and amelioration of comorbid conditions such as blood pressure and dyslipidemia in patients with T1DM who undergo weight loss surgery. However, there is little evidence to suggest significant improvement in glycemic control and lowering of glycosylated hemoglobin, and bariatric surgical procedures do not necessarily lead to enhanced diabetes management. and improved quality of life. The potential possibility of micronutrient deficiency, weight regain, and psychobehavioral issues post-bariatric surgery also exists. An individualized evaluation of the risks and benefits should be considered, using a a multidisciplinary team approach with expertise in patient selection, surgical technique, and follow-up. A crucial component is the availability of a diabetes care specialist or endocrinologist experienced in intensive, tailored, modifiable insulin regimens who maintains close and careful monitoring during all phases of management. Reliable data from a prospective, longitudinal perspective is required to provide guidelines for clinicians and informed choices for obese patients with T1DM who are contemplating bariatric surgery.

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减肥手术在 1 型糖尿病和肥胖症患者中不断演变的作用。
减肥手术已成为病态肥胖的 2 型糖尿病患者的可行治疗方案。随着社会生活方式的改变和对实现代谢目标的重视,超重和肥胖的 1 型糖尿病(T1DM)患者人数也在增加。根据数量有限的观察报告得出的初步经验表明,接受减重手术的 T1DM 患者体重大幅减轻,血压和血脂异常等并发症也有所改善。然而,几乎没有证据表明血糖控制和糖化血红蛋白的降低有明显改善,而且减肥手术并不一定能加强糖尿病管理和提高生活质量。减肥手术后还可能出现微量元素缺乏、体重反弹和心理行为问题。应考虑对风险和益处进行个体化评估,采用多学科团队方法,在患者选择、手术技术和随访方面提供专业知识。其中一个关键因素是要有糖尿病护理专家或内分泌专家,他们在强化、量身定制、可调整的胰岛素治疗方案方面经验丰富,并在治疗的各个阶段保持密切和仔细的监测。我们需要从前瞻性、纵向的角度获得可靠的数据,为临床医生提供指导,并为考虑接受减肥手术的 T1DM 肥胖患者提供明智的选择。
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