Palliation of Dysphagia in Carcinoma Esophagus.

Clinical Medicine Insights. Gastroenterology Pub Date : 2016-06-06 eCollection Date: 2016-01-01 DOI:10.4137/CGast.S30303
Vishnu Prasad Nelamangala Ramakrishnaiah, Somanath Malage, G S Sreenath, Sudhakar Kotlapati, Sunu Cyriac
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引用次数: 17

Abstract

Esophageal carcinoma has a special place in gastrointestinal carcinomas because it contains two main types, namely, squamous cell carcinoma and adenocarcinoma. Carcinoma esophagus patients require some form of palliation because of locally advanced stage or distant metastasis, where it cannot be subjected to curable treatment with surgery and chemoradiation. Many modalities of palliation of dysphagia are available, but the procedure with least morbidity, mortality, and long-term palliation of dysphagia needs to be chosen for the patient. This study aims to discuss the recent trends in palliation of dysphagia with promising results and the most suitable therapy for palliation of dysphagia in a given patient. A total of 64 articles that were published between years 2005 and 2015 on various modes of palliation of dysphagia in carcinoma esophagus were studied, which were mainly randomized and prospective studies. Through this study, we conclude that stents are the first choice of therapy for palliation, which is safe and cost-effective, and they can be combined with either radiotherapy or chemotherapy for long-term palliation of dysphagia with good quality of life. Radiotherapy can be used as a second-line treatment modality.

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食管癌患者吞咽困难的缓解。
食管癌在胃肠道癌中占有特殊的地位,因为它包含两种主要类型,即鳞状细胞癌和腺癌。食管癌患者由于局部晚期或远处转移,无法通过手术和放化疗治愈,需要某种形式的姑息治疗。有许多缓解吞咽困难的方法,但需要为患者选择发病率和死亡率最低、长期缓解吞咽困难的方法。本研究旨在讨论缓解吞咽困难的最新趋势和有希望的结果,以及缓解特定患者吞咽困难的最合适的治疗方法。本研究共纳入2005 - 2015年间发表的64篇关于食管癌吞咽困难各种缓解方式的文章,以随机和前瞻性研究为主。通过本研究,我们认为支架是缓解吞咽困难的首选治疗方法,安全、经济,可与放疗或化疗联合长期缓解吞咽困难,生活质量良好。放疗可作为二线治疗方式。
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来源期刊
Clinical Medicine Insights. Gastroenterology
Clinical Medicine Insights. Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
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审稿时长
8 weeks
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