EFFECT OF PREOPERATIVE INTRAVENOUS OXYCODONE ON LOW-DOSE ROPIVACAINE SPINAL ANESTHESIA COMBINED WITH INTRATHECAL FENTANYL.

Middle East Journal of Anesthesiology Pub Date : 2016-02-01

Na Wang, Songling Zhang, Yaowen Fu, Jinguo Wang

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Abstract

Background: Low-dose ropivacaine combined with intrathecal fentanyl can provide adequate anaesthesia with minimal haemodynamic variation. Preemptive analgesia can enhance analgesic effect of spinal anaesthesia without obvious side effects.

Aims: To assess the efficacy of preoperative intravenous oxycodone on transurethral resection of prostate (TURP) under 10 mg ropivacaine spinal anaesthesia combined with intrathecal 25 pg fentanyl.

Methods: Sixty patients undergoing TURP were randomly divided into two groups: Group o (n=30), in which the patients were administered 0.1 mg.kg-1 oxycodone intravenously 10 min prior to the operation for 2 min, and Group C (n=30) in which the patients were administered intravenously a similar volume of 0.9% saline. The participants were injected with hyperbaric 10 mg ropivacaine and 25 µg fentanyl intrathecally. The block characteristics, hemodynamic values, the tramadol consumption and adverse effects were analyzed.

Results: The peak level of sensory block was lower in Group C. Time to the first analgesic request and time to two-segment regression of sensory block were shorter in Group C. Fewer patients in Group 0 were given postoperative analgesics.

Conclusion: Preoperative intravenous oxycodone can prolong analgesic effect of this method and postoperative analgesia.

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术前静脉注射羟考酮对小剂量罗哌卡因脊髓麻醉联合鞘内芬太尼的影响。

背景:小剂量罗哌卡因联合鞘内芬太尼可以提供足够的麻醉，血流动力学变化最小。先发制人镇痛可增强脊髓麻醉的镇痛效果，且无明显的副作用。目的:评价术前静脉注射羟考酮在罗哌卡因10 mg脊髓麻醉联合芬太尼25 pg鞘内麻醉下经尿道前列腺切除术(TURP)的疗效。方法:60例TURP患者随机分为两组:o组(n=30)，每组患者给予0.1 mg;术前10分钟静脉滴注氧可酮kg-1，持续2分钟;C组(n=30)患者静脉滴注等量0.9%生理盐水。参与者在鞘内注射高压10 mg罗哌卡因和25µg芬太尼。分析阻滞特征、血流动力学值、曲马多用量及不良反应。结果:c组感觉阻滞的峰值水平较低。c组到第一次镇痛请求的时间较短，感觉阻滞两段回归的时间较短。0组术后给予镇痛药的患者较少。结论:术前静脉注射羟考酮可延长该方法的镇痛效果及术后镇痛时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Middle East Journal of Anesthesiology Medicine-Anesthesiology and Pain Medicine

CiteScore

0.20

自引率

0.00%

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期刊介绍： The journal is published three times a year (February, June, and October) and has an Editorial Executive Committee from the department and consultant editors from various Arab countries. A volume consists of six issues. Presently, it is in its 42nd year of publication and is currently in its 19th volume. It has a worldwide circulation and effective March 2008, the MEJA has become an electronic journal. The main objective of the journal is to act as a forum for publication, education, and exchange of opinions, and to promote research and publications of the Middle Eastern heritage of medicine and anesthesia.