Acceleration-selective arterial spin labeling for intracranial MR angiography with improved visualization of cortical arteries and suppression of cortical veins

IF 3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Magnetic Resonance in Medicine Pub Date : 2016-07-15 DOI:10.1002/mrm.26275

Makoto Obara, Osamu Togao, Masami Yoneyama, Tomoyuki Okuaki, Shuhei Shibukawa, Hiroshi Honda, Marc Van Cauteren

{"title":"Acceleration-selective arterial spin labeling for intracranial MR angiography with improved visualization of cortical arteries and suppression of cortical veins","authors":"Makoto Obara, Osamu Togao, Masami Yoneyama, Tomoyuki Okuaki, Shuhei Shibukawa, Hiroshi Honda, Marc Van Cauteren","doi":"10.1002/mrm.26275","DOIUrl":null,"url":null,"abstract":"<div>\n \n <section>\n \n <h3> Purpose</h3>\n \n <p>A new approach for intracranial MR angiography (MRA) is introduced, using acceleration-selective arterial spin labeling (AccASL). The aim of this study was to investigate the arterial visualization and venous suppression using AccASL.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Intracranial MRA images obtained by AccASL and time-of-flight (TOF) were compared in seven healthy volunteers and one patient with occlusion of the terminal portion of the left internal carotid artery. The volunteer images were assessed by measuring the contrast-to-noise ratio (CNR) between the middle cerebral artery (MCA) and white matter (WM) and between the confluence of sinuses and WM. Additionally, visualized peripheral arteries were counted and qualitative scoring of the MCA visualization and vein signal contamination was conducted.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The CNR at the M4 branch and the number of visualized arteries was significantly higher using AccASL compared with that in TOF (<i>P</i> < 0.05). In the qualitative comparison, the score for artery visualization was higher using AccASL (<i>P</i> < 0.05), while minimizing signal contamination by cortical veins. Additionally, in patient examination, the collateral flow visualization was better with AccASL.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>AccASL enables better efficiency for visualizing peripheral arteries compared with TOF, while suppressing cortical vein signal. Magn Reson Med 77:1996–2004, 2017. © 2016 International Society for Magnetic Resonance in Medicine</p>\n </section>\n </div>","PeriodicalId":18065,"journal":{"name":"Magnetic Resonance in Medicine","volume":"77 5","pages":"1996-2004"},"PeriodicalIF":3.0000,"publicationDate":"2016-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mrm.26275","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magnetic Resonance in Medicine","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/mrm.26275","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 12

Abstract

Purpose

A new approach for intracranial MR angiography (MRA) is introduced, using acceleration-selective arterial spin labeling (AccASL). The aim of this study was to investigate the arterial visualization and venous suppression using AccASL.

Methods

Intracranial MRA images obtained by AccASL and time-of-flight (TOF) were compared in seven healthy volunteers and one patient with occlusion of the terminal portion of the left internal carotid artery. The volunteer images were assessed by measuring the contrast-to-noise ratio (CNR) between the middle cerebral artery (MCA) and white matter (WM) and between the confluence of sinuses and WM. Additionally, visualized peripheral arteries were counted and qualitative scoring of the MCA visualization and vein signal contamination was conducted.

Results

The CNR at the M4 branch and the number of visualized arteries was significantly higher using AccASL compared with that in TOF (P < 0.05). In the qualitative comparison, the score for artery visualization was higher using AccASL (P < 0.05), while minimizing signal contamination by cortical veins. Additionally, in patient examination, the collateral flow visualization was better with AccASL.

Conclusion

AccASL enables better efficiency for visualizing peripheral arteries compared with TOF, while suppressing cortical vein signal. Magn Reson Med 77:1996–2004, 2017. © 2016 International Society for Magnetic Resonance in Medicine

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

加速选择性动脉自旋标记颅内磁共振血管造影，改善皮质动脉的可视化和皮质静脉的抑制

目的介绍一种新的颅内磁共振血管造影(MRA)方法——加速选择性动脉自旋标记(AccASL)。本研究的目的是探讨AccASL的动脉显像和静脉抑制。方法对7名健康志愿者和1例左颈内动脉末端闭塞患者的AccASL和TOF颅内MRA图像进行比较。通过测量大脑中动脉(MCA)与脑白质(WM)之间以及鼻窦与脑白质汇合处之间的对比噪声比(CNR)对志愿者图像进行评估。此外，对显示的外周动脉进行计数，并对MCA显示和静脉信号污染进行定性评分。结果与TOF组相比，AccASL组M4支的CNR和可见动脉数量显著增加(P < 0.05)。在定性比较中，AccASL对动脉显示的评分更高(P < 0.05)，同时最大限度地减少了皮质静脉的信号污染。此外，在患者检查中，AccASL的侧支血流显示效果更好。结论与TOF相比，AccASL能更好地显示外周动脉，同时抑制皮质静脉信号。中华医学杂志(英文版):1996 - 2004,2017。©2016国际医学磁共振学会

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Magnetic Resonance in Medicine 医学-核医学

CiteScore

6.70

自引率

24.20%

发文量

376

审稿时长

2-4 weeks

期刊介绍： Magnetic Resonance in Medicine (Magn Reson Med) is an international journal devoted to the publication of original investigations concerned with all aspects of the development and use of nuclear magnetic resonance and electron paramagnetic resonance techniques for medical applications. Reports of original investigations in the areas of mathematics, computing, engineering, physics, biophysics, chemistry, biochemistry, and physiology directly relevant to magnetic resonance will be accepted, as well as methodology-oriented clinical studies.