Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer.

Valentina Villano, Chiara Stella Di Stadio, Antonella Federico, Filomena Altieri, Giuseppina Miselli, Maurizio De Palma, Emilia Rippa, Paolo Arcari
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引用次数: 5

Abstract

Background: We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.

Results: Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals.

Conclusions: Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.

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人血清胃因子1mrna不是胃癌的信息性生物标志物。
背景:我们的目的是确定胃癌患者血清中胃因子1mrna是否可能是该疾病的信息生物标志物。结果:采用基于标准曲线法的绝对定量分析,健康人(n = 23)和胃癌确诊患者(n = 16)血清样本中GKN1 mRNA含量,两组未配对个体间差异无统计学意义。结论:我们的初步结果没有证实GKN1是胃癌的潜在生物标志物。
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