Audrey Benoit, Philippe-Olivier Harvey, Louis Bherer, Martin Lepage
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引用次数: 35
Abstract
Cognitive remediation therapy (CRT) has emerged as a viable treatment option for people diagnosed with schizophrenia presenting disabling cognitive deficits. However, it is important to determine which variables can influence response to CRT in order to provide cost-effective treatment. This study's aim was to explore cognitive insight as a potential predictor of cognitive improvement after CRT. Twenty patients with schizophrenia completed a 24-session CRT program involving 18 hours of computer exercises and 6 hours of group discussion to encourage generalization of cognitive training to everyday activities. Pre- and posttest assessments included the CogState Research Battery and the Beck Cognitive Insight Scale (BCIS). Lower self-certainty on the BCIS at baseline was associated with greater improvement in speed of processing (r s = -0.48; p < 0.05) and visual memory (r s = -0.46; p < 0.05). The results of this study point out potential associations between self-certainty and cognitive improvement after CRT, a variable that can easily be measured in clinical settings to help evaluate which patients may benefit most from the intervention. They also underline the need to keep investigating the predictors of good CRT outcomes, which can vary widely between patients.
认知修复疗法(CRT)已成为精神分裂症患者的一种可行的治疗选择。然而,为了提供具有成本效益的治疗,确定哪些变量会影响对CRT的反应是很重要的。本研究的目的是探索认知洞察力作为CRT后认知改善的潜在预测因子。20名精神分裂症患者完成了一个24期的CRT项目,其中包括18小时的电脑练习和6小时的小组讨论,以鼓励将认知训练推广到日常活动中。测试前和测试后的评估包括CogState Research Battery和Beck认知洞察力量表(BCIS)。基线时BCIS的自我确定性较低与处理速度的较大改善相关(r s = -0.48;P < 0.05)和视觉记忆(r s = -0.46;P < 0.05)。这项研究的结果指出了自我确定性与CRT后认知改善之间的潜在关联,这是一个在临床环境中很容易测量的变量,可以帮助评估哪些患者可能从干预中获益最多。他们还强调有必要继续研究良好CRT结果的预测因素,这在不同患者之间可能有很大差异。
期刊介绍:
Schizophrenia Research and Treatment is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to all aspects of schizophrenia.