The Legacy of Genetic Analysis Advances Contemporary Research with Escherichia coli K-12 and Salmonella enterica serovar Typhimurium LT2.

Q1 Medicine EcoSal Plus Pub Date : 2017-04-01 DOI:10.1128/ecosalplus.ESP-0014-2016
Valley Stewart
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Abstract

Escherichia coli K-12 and Salmonella enterica serovar Typhimurium LT2 became standard organisms for genetic analysis during the Truman administration. Half a century later, genetic analysis with these strains had become an art form, interpreted through 23 articles in the ambitious two-volume masterpiece edited by the late Fred Neidhardt and colleagues. These legacy articles now are available through EcoSal Plus, so as to inform and inspire contemporary genetic analyses in these standard organisms and their relatives.

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遗传分析的遗产推进了大肠杆菌K-12和肠沙门氏菌血清型鼠伤寒杆菌LT2的当代研究。
在杜鲁门执政期间,大肠杆菌K-12和肠沙门氏菌血清型鼠伤寒杆菌LT2成为基因分析的标准生物。半个世纪后,对这些菌株的基因分析已经成为一种艺术形式,由已故的弗雷德·内德哈特(Fred Neidhardt)及其同事编辑的雄心勃勃的两卷本杰作中,通过23篇文章进行了阐释。这些遗产文章现在可以通过ecsal Plus获得,以便为这些标准生物及其亲属的当代遗传分析提供信息和启发。
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来源期刊
EcoSal Plus
EcoSal Plus Immunology and Microbiology-Microbiology
CiteScore
12.20
自引率
0.00%
发文量
4
期刊介绍: EcoSal Plus is the authoritative online review journal that publishes an ever-growing body of expert reviews covering virtually all aspects of E. coli, Salmonella, and other members of the family Enterobacteriaceae and their use as model microbes for biological explorations. This journal is intended primarily for the research community as a comprehensive and continuously updated archive of the entire corpus of knowledge about the enteric bacterial cell. Thoughtful reviews focus on physiology, metabolism, genetics, pathogenesis, ecology, genomics, systems biology, and history E. coli and its relatives. These provide the integrated background needed for most microbiology investigations and are essential reading for research scientists. Articles contain links to E. coli K12 genes on the EcoCyc database site and are available as downloadable PDF files. Images and tables are downloadable to PowerPoint files.
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