Optical coherence tomography of the preterm eye: from retinopathy of prematurity to brain development.

IF 3.1 Q1 OPHTHALMOLOGY Eye and Brain Pub Date : 2016-05-27 eCollection Date: 2016-01-01 DOI:10.2147/EB.S97660
Adam L Rothman, Shwetha Mangalesh, Xi Chen, Cynthia A Toth
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引用次数: 15

Abstract

Preterm infants with retinopathy of prematurity are at increased risk of poor neurodevelopmental outcomes. Because the neurosensory retina is an extension of the central nervous system, anatomic abnormalities in the anterior visual pathway often relate to system and central nervous system health. We describe optical coherence tomography as a powerful imaging modality that has recently been adapted to the infant population and provides noninvasive, high-resolution, cross-sectional imaging of the infant eye at the bedside. Optical coherence tomography has increased understanding of normal eye development and has identified several potential biomarkers of brain abnormalities and poorer neurodevelopment.

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早产儿眼的光学相干断层扫描:从早产儿视网膜病变到大脑发育。
患有早产儿视网膜病变的早产儿神经发育不良的风险增加。由于神经感觉视网膜是中枢神经系统的延伸,前视通路的解剖异常通常与系统和中枢神经系统健康有关。我们将光学相干断层扫描描述为一种强大的成像方式,最近已适应于婴儿人群,并提供床边婴儿眼睛的无创,高分辨率,横断面成像。光学相干断层扫描增加了对正常眼睛发育的理解,并确定了大脑异常和较差神经发育的几个潜在生物标志物。
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来源期刊
Eye and Brain
Eye and Brain OPHTHALMOLOGY-
CiteScore
7.90
自引率
2.30%
发文量
12
审稿时长
16 weeks
期刊介绍: Eye and Brain is an international, peer-reviewed, open access journal focusing on basic research, clinical findings, and expert reviews in the field of visual science and neuro-ophthalmology. The journal’s unique focus is the link between two well-known visual centres, the eye and the brain, with an emphasis on the importance of such connections. All aspects of clinical and especially basic research on the visual system are addressed within the journal as well as significant future directions in vision research and therapeutic measures. This unique journal focuses on neurological aspects of vision – both physiological and pathological. The scope of the journal spans from the cornea to the associational visual cortex and all the visual centers in between. Topics range from basic biological mechanisms to therapeutic treatment, from simple organisms to humans, and utilizing techniques from molecular biology to behavior. The journal especially welcomes primary research articles or review papers that make the connection between the eye and the brain. Specific areas covered in the journal include: Physiology and pathophysiology of visual centers, Eye movement disorders and strabismus, Cellular, biochemical, and molecular features of the visual system, Structural and functional organization of the eye and of the visual cortex, Metabolic demands of the visual system, Diseases and disorders with neuro-ophthalmic manifestations, Clinical and experimental neuro-ophthalmology and visual system pathologies, Epidemiological studies.
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