Late onset pulmonary metastasis more than 10 years after primary sigmoid carcinoma.

Anne M Daniels, Jeroen F J Vogelaar
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引用次数: 4

Abstract

According to current guidelines, follow-up of patients with colorectal cancer is ended after five years. Also, chest X-ray is not part of standard investigation during follow-up. We describe a case of a 74-year-old patient, more than ten years after a sigmoid resection because of carcinoma of the sigmoid. No recurrence was detected during intensive follow-up. However, ten years after resection of the sigmoid adenocarcinoma, complaints of coughing induced further examination with as result the detection of a solitary metastasis in the left lung of the patient. Within half-a-year after metastasectomy of the lung metastasis, she presented herself with thoracic pain and dyspnea resulting in discovering diffuse metastasis on pulmonary, pleural, costal and muscular level. Five year follow-up of colorectal carcinoma without chest X-ray can be questioned to be efficient. The growing knowledge of tumor biology might in future adjust the duration and frequency of diagnostic follow-up to prevent (late) recurrence in patients with colorectal carcinoma.

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原发性乙状结肠癌后10年以上迟发性肺转移。
根据目前的指南,结直肠癌患者的随访在5年后结束。此外,胸部x光也不是随访期间标准调查的一部分。我们描述了一个病例74岁的病人,超过十年后乙状结肠切除术,因为乙状结肠癌。强化随访无复发。然而,在乙状腺癌切除十年后,咳嗽的主诉引起了进一步的检查,结果在患者的左肺发现了一个孤立的转移。患者在肺转移灶切除半年内出现胸痛、呼吸困难,发现肺、胸膜、肋、肌等部位弥漫性转移。结直肠癌5年随访不做胸部x线检查是否有效值得质疑。随着肿瘤生物学知识的不断增长,将来可能会调整诊断随访的时间和频率,以预防结直肠癌患者的(晚期)复发。
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