[[The Pathogenetic Approaches to the Chronic Liver Diseases Treatment].]

E V Golovanova
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Abstract

The paper reflects the issues of pathogenesis of the chronic liver diseases (CLD). The role of the cell membrane lipid peroxidation as well as oxidative stress and fibrosis formation in the development and progression of liver lesions of various aetiologies. are represented in details. Particular attention is given to the justification of pathogenetic approaches to the treatment of liver disease. Presented the evidence base of successful application of the standardized silymarin as a part of the drug Legalon in the CLD of different etiology.

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慢性肝病的病因学治疗方法[j]。
本文就慢性肝病(CLD)的发病机制问题作一综述。细胞膜脂质过氧化以及氧化应激和纤维化形成在各种病因的肝脏病变的发生和进展中的作用。都有详细说明。特别注意的是,病理方法的理由,以治疗肝病。介绍了标准水飞蓟素作为药物Legalon的一部分在不同病因的CLD中成功应用的证据基础。
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