The antioxidant effect of Beackea frutescence microemulsions dietary supplements on skin absorption studies.

Acta Biomaterialia Odontologica Scandinavica Pub Date : 2016-07-22 eCollection Date: 2016-12-01 DOI:10.1080/23337931.2016.1209078
Mohd Zul Helmi Rozaini, Armiza Ahmad, Azizul Idris, Chen Fei Low, Mohd Effendy Abdul Wahid
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Abstract

Objective: To study the effect of two different microemulsions containing Beackea frutescence supplements composed of nerolidool, selenium and vitamin E on absorption effect related to skin health and skin aging. Materials and methods: A total of 39 volunteers with normal and healthy skin were divided into three groups (n = 13) and supplemented for a period of 12 weeks. Group 1 received a mixture of lutein (3 mg/day), lycopene (3 mg/day), α-tocopherol (10 mg/day), selenium (75 μg/day) and β-nerolidool (4.8 mg/day) and Group 2 was supplemented with a mixture of β-nerolidool (4.8 mg/day), lycopene (6 mg/day), selenium (75 μg/day) and α-tocopherol (10 mg/day). Group 3 was the placebo control. Wrinkling, smoothness, scaling and roughness of the skin were determined by Surface Evaluation of Living Skin (Visioscan). Results: Upon supplementation, serum levels of selected nerolidool increased in both groups. Skin thickness and density were determined by ultrasound measurements. A significant increase for both parameters was determined in the serum groups. Roughness and scaling were improved by the supplementation with antioxidant micronutrients. In the placebo group, no changes were found for any of the parameters. Conclusion:Beackeafrutescence microemulsion supplements have shown significant change in the texture of human skin as well as scaling, wrinkling, smoothness and roughness were improved by the supplementation.

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槟榔微乳膳食补充剂对皮肤吸收的抗氧化作用研究。
目的:研究两种不同的由橙花醇、硒和维生素E组成的槟榔微乳对与皮肤健康和皮肤衰老相关的吸收效果的影响。材料与方法:将39名皮肤正常健康的志愿者分为3组(n = 13),每组补充12周。组1饲喂叶黄素(3 mg/d)、番茄红素(3 mg/d)、α-生育酚(10 mg/d)、硒(75 μg/d)和β-橙油醇(4.8 mg/d)的混合饲粮,组2饲喂β-橙油醇(4.8 mg/d)、番茄红素(6 mg/d)、硒(75 μg/d)和α-生育酚(10 mg/d)的混合饲粮。第三组为安慰剂对照组。用活体皮肤表面评价(Visioscan)测定皮肤的起皱、光滑、结垢和粗糙度。结果:补充后,两组血清中所选神经醇的水平均升高。通过超声测量皮肤厚度和密度。在血清组中,这两个参数都有显著的增加。添加抗氧化微量营养素可改善表面粗糙度和结垢。在安慰剂组中,没有发现任何参数的变化。结论:微乳剂能显著改变人体皮肤的质地,改善皮肤的结垢、起皱、光滑度和粗糙度。
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