An Exploratory Study of Autonomic Function Investigations in Hemophiliacs on Homoeopathy Medications Using Impedance Plethysmography.

Tapas K Kundu, Pradip B Barde, Ghanshyam D Jindal, Farooq F Motiwala
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引用次数: 1

Abstract

Background: Status of autonomic homoeostasis in hemostasic disturbances due to hemophilia needs to be studied.

Objectives: To compare autonomic nervous system markers measured by heart rate variability (HRV) and blood flow variability (BFV) in hemophiliacs and healthy age-matched control population using medical analyzer system.

Design: Cross-sectional study.

Settings: Motiwala Homoeopathy Medical College, and Hemophilia Clinics, Nashik.

Subjects: Eighty subjects.

Interventions: Nil.

Outcome measures: Autonomic function markers for HRV and BFV.

Results: Among 80 subjects, BFV time domain measure, root mean square of successive NN (normal-to-normal) interval differences (RMSSD), was significantly higher among hemophiliacs than nonhemophiliacs. Frequency domain analysis parameter, low frequency for both HRV and BFV was significantly higher among hemophiliacs as compared with nonhemophiliacs.

Conclusions: Hemophiliacs were shown to have higher autonomic activity as compared with healthy controls. Homoeopathic medicines used as an adjunct was associated with decrease in parasympathetic modulations.

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利用阻抗容积描记术对血友病患者使用顺势药物后自主神经功能的探索性研究。
背景:血友病引起的止血障碍中自主神经平衡的状态需要进一步研究。目的:比较血友病患者与健康对照人群心率变异性(HRV)和血流变异性(BFV)测量的自主神经系统指标。设计:横断面研究。环境:Motiwala顺势疗法医学院和血友病诊所,纳西克。受试者:80名受试者。干预措施:零。结果测量:HRV和BFV的自主功能标记物。结果:80例受试者中,血友病患者的BFV时域测量值(连续NN (normal- normal) interval difference, RMSSD)的均方根值显著高于非血友病患者。频域分析参数显示,血友病患者HRV和BFV的低频均明显高于非血友病患者。结论:与健康对照相比,血友病患者显示出更高的自主神经活动。顺势疗法药物用作辅助药物与副交感神经调节的减少有关。
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期刊介绍: The Journal of Evidence-Based Integrative Medicine ((JEBIM)), published previously as the Journal of Evidence-Based Complementary and Alternative Medicine (JEBCAM) and also as Complementary Health Practice Review (CHPR). The Journal of Evidence-Based Integrative Medicine (JEBIM) is an interdisciplinary, peer-reviewed, open access, biomedical journal whose aim is to create a global platform for hypothesis-driven and evidence-based research in all fields of integrative medicine. The journal’s objective is to publish papers which impart scientific validity to Integrative Medicine methods that are indispensable and inevitable in today’s world. All papers will be peer reviewed by experts in their respective fields, and papers will be accepted based on their scientific merit. It is the goal of the Journal to help remove the “myth” and provide scientific rationale for the various methodologies and theories of Integrative Medicine. All submissions will be reviewed based on their scientific merit and only papers with sound study design, valid statistical analyses and logical conclusions will be accepted. Topics include, but are not limited to: Traditional Eastern and Western medicine Nutrition therapy and supplementation Massage Therapy Non-traditional treatments Preventative medicine Integrative health and medicine Mindfulness Yoga.
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