Association between body mass index and osteoporosis in women from northwestern Rio Grande do Sul

Letícia Mazocco , Patrícia Chagas
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引用次数: 7

Abstract

Objective

To investigate the association between body mass index (BMI) and bone mineral density (BMD) in postmenopausal women.

Methods

Observational study with postmenopausal women who underwent bone densitometry in Palmeira das Missões – RS. Sociodemographic data, risk for osteoporosis and food intake were assessed through a specific form. BMI was calculated according to WHO criteria. The assessment of BMD was performed by dual-energy X-ray absorptiometry (DXA) and classified according to WHO. Statistical analysis was performed using prevalence ratios (PR) and their respective 95% confidence intervals for the factors studied. Variables associated with p < 0.20 with the different outcomes (osteopenia and osteoporosis) were included in a Poisson regression model with robust variance to adjust for potential confounding factors. A 5% significance level was considered.

Results

393 postmenopausal women with a mean age of 59.6 ± 8.2 years participated.

After the adjustments, the normal weight women had 1.2 times the prevalence of osteopenia of obese women (PR = 1.2; CI 95% 1.3–1.5). Considering osteoporosis, the PR of euthophic women was twice the PR of obese women (PR = 2; CI 95% 1.4–2.9) and was 1.7 times greater for overweight group compared to obese category (PR = 1.7; CI 95% 1.2–2.5).

Conclusion

Obese women had lower prevalence of osteopenia compared with normal weight subjects and also with lower prevalence of osteoporosis as compared to normal- and overweight women.

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南里奥格兰德州西北部妇女体重指数与骨质疏松症的关系
目的探讨绝经后妇女体重指数(BMI)与骨密度(BMD)的关系。方法对在Palmeira das Missões - RS接受骨密度测量的绝经后妇女进行观察性研究,通过特定表格评估社会人口统计学数据、骨质疏松风险和食物摄入。BMI是根据WHO标准计算的。采用双能x线骨密度仪(DXA)评估骨密度,并按WHO分级。采用患病率(PR)及其各自的95%置信区间对所研究的因素进行统计分析。p <相关变量;0.20的不同结果(骨质减少和骨质疏松)纳入稳健方差的泊松回归模型,以调整潜在的混杂因素。考虑5%的显著性水平。结果绝经后妇女393例,平均年龄59.6±8.2岁。调整后,正常体重女性骨质减少的患病率是肥胖女性的1.2倍(PR = 1.2;Ci 95% 1.3-1.5)。考虑骨质疏松,健康女性的PR是肥胖女性的2倍(PR = 2;CI 95% 1.4-2.9),超重组是肥胖组的1.7倍(PR = 1.7;Ci 95% 1.2-2.5)。结论与正常体重的女性相比,肥胖女性骨质减少的患病率较低,骨质疏松症的患病率也较正常和超重女性低。
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