ANTI-VIRAL EFFECTS OF MEDICINAL PLANTS IN THE MANAGEMENT OF DENGUE: A SYSTEMATIC REVIEW.

Éric Heleno Freira Ferreira Frederico, André Luiz Bandeira Dionísio Cardoso, Eloá Moreira-Marconi, Danúbia da Cunha de Sá-Caputo, Carlos Alberto Sampaio Guimarães, Carla da Fontoura Dionello, Danielle Soares Morel, Laisa Liane Paineiras-Domingos, Patricia Lopes de Souza, Samuel Brandão-Sobrinho-Neto, Rafaelle Pacheco Carvalho-Lima, Eliane de Oliveira Guedes-Aguiar, Rebeca Graça Costa-Cavalcanti, Cristiane Ribeiro Kutter, Mario Bernardo-Filho
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引用次数: 14

Abstract

Background: Dengue is considered as an important arboviral disease. Safe, low-cost, and effective drugs that possess inhibitory activity against dengue virus (DENV) are mostly needed to try to combat the dengue infection worldwide. Medicinal plants have been considered as an important alternative to manage several diseases, such as dengue. As authors have demonstrated the antiviral effect of medicinal plants against DENV, the aim of this study was to review systematically the published research concerning the use of medicinal plants in the management of dengue using the PubMed database.

Materials and methods: Search and selection of publications were made using the PubMed database following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA statement).

Results: Six publications met the inclusion criteria and were included in the final selection after thorough analysis.

Conclusion: It is suggested that medicinal plants' products could be used as potential anti-DENV agents.

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药用植物在登革热防治中的抗病毒作用:系统综述。
背景:登革热被认为是一种重要的虫媒病毒性疾病。在世界范围内防治登革热感染最需要的是具有登革热病毒抑制活性的安全、低成本和有效的药物。药用植物已被认为是管理登革热等几种疾病的重要替代方法。由于作者已经证明了药用植物对登革热病毒的抗病毒作用,本研究的目的是利用PubMed数据库系统地回顾有关药用植物在登革热管理中的应用的已发表的研究。材料和方法:根据系统评价和荟萃分析首选报告项目(PRISMA声明)的指导方针,使用PubMed数据库进行出版物的搜索和选择。结果:6篇文献符合纳入标准,经全面分析后最终入选。结论:药用植物制剂可作为潜在的抗denv药物。
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