Effect of Exercise Intervention on Flow-Mediated Dilation in Overweight and Obese Adults: Meta-Analysis.

IF 2.5 Q2 PERIPHERAL VASCULAR DISEASE International Journal of Vascular Medicine Pub Date : 2017-01-01 Epub Date: 2017-10-01 DOI:10.1155/2017/7532702

Younsun Son, Kyungun Kim, Soeun Jeon, Minsoo Kang, Sukho Lee, Yoonjung Park

{"title":"Effect of Exercise Intervention on Flow-Mediated Dilation in Overweight and Obese Adults: Meta-Analysis.","authors":"Younsun Son, Kyungun Kim, Soeun Jeon, Minsoo Kang, Sukho Lee, Yoonjung Park","doi":"10.1155/2017/7532702","DOIUrl":null,"url":null,"abstract":"The objective of this meta-analysis is to summarize the effect of exercise intervention on flow-mediated dilatation (FMD) in overweight and obese adults. We searched four electronic databases (PubMed/Medline, Scopus, and CINAHL) through June 2016 for relevant studies pertaining to the effectiveness of exercise intervention on FMD. Seventeen of the 91 studies identified met the inclusion criteria. Comprehensive Meta-Analysis software (version 3) was used to compute the standardized mean difference effect size (ES) and 95% CI using a random effects model. We calculated 34 ESs. We found that exercise intervention had medium and positive effects on FMD, with an overall ES of 0.522 (95% CI = 0.257, 0.786). Heterogeneity of ESs was observed (Qb = 239, p ≤ 0.001, I2 = 86.19), and the effect was moderated by comorbidity (Qb = 6.39, df = 1, p = 0.011). A large ES for the combination exercise, low intensity exercise, and comorbidity subgroups (ES = 0.82~1.24) was found. We conclude that while exercise intervention significantly improves FMD in overweight and obese adults, the effect may depend on the different characteristics of exercise intervention and on participants' demographics.","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":"2017 ","pages":"7532702"},"PeriodicalIF":2.5000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/7532702","citationCount":"15","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Vascular Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2017/7532702","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/10/1 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}

引用次数: 15

Abstract

The objective of this meta-analysis is to summarize the effect of exercise intervention on flow-mediated dilatation (FMD) in overweight and obese adults. We searched four electronic databases (PubMed/Medline, Scopus, and CINAHL) through June 2016 for relevant studies pertaining to the effectiveness of exercise intervention on FMD. Seventeen of the 91 studies identified met the inclusion criteria. Comprehensive Meta-Analysis software (version 3) was used to compute the standardized mean difference effect size (ES) and 95% CI using a random effects model. We calculated 34 ESs. We found that exercise intervention had medium and positive effects on FMD, with an overall ES of 0.522 (95% CI = 0.257, 0.786). Heterogeneity of ESs was observed (Q_b = 239, p ≤ 0.001, I² = 86.19), and the effect was moderated by comorbidity (Q_b = 6.39, df = 1, p = 0.011). A large ES for the combination exercise, low intensity exercise, and comorbidity subgroups (ES = 0.82~1.24) was found. We conclude that while exercise intervention significantly improves FMD in overweight and obese adults, the effect may depend on the different characteristics of exercise intervention and on participants' demographics.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

运动干预对超重和肥胖成人血流介导的舒张的影响:meta分析。

本荟萃分析的目的是总结运动干预对超重和肥胖成人血流介导扩张(FMD)的影响。截至2016年6月，我们检索了四个电子数据库(PubMed/Medline, Scopus和CINAHL)，以获取有关运动干预FMD有效性的相关研究。91项研究中有17项符合纳入标准。采用综合meta分析软件(version 3)，采用随机效应模型计算标准化平均差异效应大小(ES)和95% CI。我们计算了34ess。我们发现运动干预对FMD有中等和积极的影响，总体ES为0.522 (95% CI = 0.257, 0.786)。ESs存在异质性(Qb = 239, p≤0.001,I2 = 86.19)，合并症可缓解ESs的影响(Qb = 6.39, df = 1, p = 0.011)。联合运动、低强度运动和合并症亚组的ES值较大(ES = 0.82~1.24)。我们的结论是，虽然运动干预可以显著改善超重和肥胖成年人的FMD，但效果可能取决于运动干预的不同特征和参与者的人口统计学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊