{"title":"Pharmacokinetics of digoxin in C.A.P.D.","authors":"M De Paepe, F Belpaire, Y Bogaerts","doi":"10.3109/08860228209050814","DOIUrl":null,"url":null,"abstract":"<p><p>The peritoneal elimination of digoxin during C.A.P.D. was studied in five patients. The plasma half life of digoxin varied from 54 hours to 141 hours. Only 7 to 24 micrograms was eliminated via the peritoneal route during 3 to 4 days C.A.P.D. treatment. The total urinary elimination during the same period ranged from 11 to 57 micrograms. It is concluded that adjustment of dose is not necessary when starting C.A.P.D.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209050814","citationCount":"11","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and experimental dialysis and apheresis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/08860228209050814","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11
Abstract
The peritoneal elimination of digoxin during C.A.P.D. was studied in five patients. The plasma half life of digoxin varied from 54 hours to 141 hours. Only 7 to 24 micrograms was eliminated via the peritoneal route during 3 to 4 days C.A.P.D. treatment. The total urinary elimination during the same period ranged from 11 to 57 micrograms. It is concluded that adjustment of dose is not necessary when starting C.A.P.D.
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