"Genetic code" of brain ageing.

Pentti Tienari, Liisa Myllykangas
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Abstract

Neurons are more susceptible than other cells to the effects of ageing, since most of them are not capable of dividing, and they consume plenty of energy. In the "genetic code of brain ageing", central role is played by the genes that regulate the risk of Alzheimer's disease and vascular diseases. Genes have been recognized underlying memory disorders and longevity. Genetic studies have revealed metabolic routes, including fat and energy metabolism, that can be influenced by an individual through living habits, and also through structures maintaining social activity.

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大脑衰老的“遗传密码”。
神经元比其他细胞更容易受到衰老的影响,因为它们中的大多数不能分裂,而且它们消耗大量的能量。在“大脑衰老的遗传密码”中,调节阿尔茨海默病和血管疾病风险的基因起着核心作用。基因已经被认为是记忆障碍和长寿的基础。遗传研究揭示了代谢途径,包括脂肪和能量代谢,可以通过个人的生活习惯和维持社会活动的结构受到影响。
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