Nonalcoholic Fatty Liver Disease in Diabetics: The Role of Hepatologist.

Reshu Khandelwal, Anuradha Supun Dassanayake, Shivaram Prasad Singh
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Abstract

Diabetes mellitus is one of the most prevalent metabolic diseases worldwide, causing an enormous burden on the economies of both developed and developing nations. Nonalcoholic fatty liver disease (NAFLD) is very closely associated with diabetes, and the two diseases are known to cause an increase in morbidity and mortality. Timely referral of a diabetic with NAFLD to a hepatologist can definitely delay disease progression and the related complications. Despite the magnitude, there are no guidelines that recommend a screening algorithm that must be followed for evaluating NAFLD in at-risk diabetics at the primary care level and their further referral to hepatologists. Nonalcoholic fatty liver disease management needs heightened awareness among primary care physicians/endocrinologists and hepatologists, and a collaborative care approach is paramount in these patients. Certain antidiabetic drugs are found to be beneficial in the treatment of NAFLD patients with diabetes, however, none of them are FDA approved.

How to cite this article: Khandelwal R, Dassanayake AS, Singh SP. Nonalcoholic Fatty Liver Disease in Diabetics: The Role of Hepatologist. Euroasian J Hepato-Gastroenterol 2022;12(Suppl 1):S37-S40.

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糖尿病患者的非酒精性脂肪性肝病:肝病学家的作用
糖尿病是世界上最常见的代谢性疾病之一,给发达国家和发展中国家的经济造成了巨大的负担。非酒精性脂肪性肝病(NAFLD)与糖尿病密切相关,已知这两种疾病会导致发病率和死亡率增加。糖尿病NAFLD的及时转诊到肝病学家可以肯定地延缓疾病进展和相关并发症。尽管如此,目前还没有指南推荐一种筛查算法,用于在初级保健水平评估高危糖尿病患者的NAFLD并进一步转诊给肝病学家。非酒精性脂肪性肝病的管理需要提高初级保健医生/内分泌学家和肝病学家的认识,在这些患者中,协作治疗方法是至关重要的。某些抗糖尿病药物被发现对NAFLD合并糖尿病患者的治疗有益,然而,这些药物都没有得到FDA的批准。引用本文:Khandelwal R, Dassanayake AS, Singh SP.非酒精性脂肪肝在糖尿病患者中的作用。中华肝病与胃肠病杂志,2022;12(增刊1):337 - s40。
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