Serum magnesium and calcium in preeclampsia: a comparative study at the Korle-Bu Teaching Hospital, Ghana.

IF 1.5 Q3 PERIPHERAL VASCULAR DISEASE Integrated Blood Pressure Control Pub Date : 2017-08-16 eCollection Date: 2017-01-01 DOI:10.2147/IBPC.S129106
Ebenezer Owusu Darkwa, Charles Antwi-Boasiako, Robert Djagbletey, Christian Owoo, Samuel Obed, Daniel Sottie
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引用次数: 34

Abstract

Background: A large percentage (16% of maternal mortality in developed countries, compared to 9% in developing countries), is due to hypertensive disorders in pregnancy. The etiology of preeclampsia remains unknown, with poorly understood pathophysiology. Magnesium and calcium play an important role in vascular smooth muscle function and therefore a possible role in the development of preeclampsia.

Aim: We aimed to compare serum magnesium and total calcium levels of preeclamptic and normal pregnant women at the Korle-Bu Teaching Hospital in Ghana.

Patients and methods: A comparative cross-sectional study involving 30 normal pregnant and 30 preeclamptic women with >30 weeks gestation and aged 18-35 years, was conducted at the Korle-Bu Teaching Hospital. Magnesium and calcium were determined using a flame atomic absorption spectrometer.

Results: Mean serum magnesium and total calcium levels in preeclamptic women were 0.70±0.15 and 2.13±0.30 mmol/L, respectively. Mean serum magnesium and total calcium levels in normal pregnant women were 0.76±0.14 and 2.13±0.35 mmol/L, respectively. There was a statistically nonsignificant difference in serum magnesium and total calcium in preeclamptic women compared to normal pregnant women, with p-values of 0.092 and 0.972, respectively.

Conclusion: Serum magnesium and total calcium, therefore, seem not to differ in preeclamptic women compared to normal pregnant women in Ghana.

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子痫前期血清镁和钙:加纳Korle-Bu教学医院的比较研究
背景:很大比例(发达国家孕产妇死亡率为16%,而发展中国家为9%)是由于妊娠期高血压疾病。子痫前期的病因尚不清楚,病理生理学也知之甚少。镁和钙在血管平滑肌功能中起重要作用,因此可能在子痫前期的发展中起作用。目的:我们的目的是比较加纳Korle-Bu教学医院子痫前期和正常孕妇的血清镁和总钙水平。患者和方法:在Korle-Bu教学医院进行了一项比较横断面研究,涉及30名妊娠>30周的正常孕妇和30名年龄在18-35岁的子痫前期妇女。镁、钙用火焰原子吸收光谱仪测定。结果:子痫前期妇女平均血清镁和总钙水平分别为0.70±0.15和2.13±0.30 mmol/L。正常孕妇血清镁和总钙水平分别为0.76±0.14和2.13±0.35 mmol/L。子痫前期妇女血清镁、总钙与正常孕妇比较,差异无统计学意义,p值分别为0.092、0.972。结论:因此,在加纳,与正常孕妇相比,子痫前期妇女的血清镁和总钙似乎没有差异。
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来源期刊
Integrated Blood Pressure Control
Integrated Blood Pressure Control PERIPHERAL VASCULAR DISEASE-
CiteScore
4.60
自引率
0.00%
发文量
13
审稿时长
16 weeks
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