Does intravenous tranexamic acid reduce blood loss during surgically assisted rapid palatal expansion?

Journal of Istanbul University Faculty of Dentistry Pub Date : 2017-10-02 eCollection Date: 2017-01-01 DOI:10.17096/jiufd.94203

Emine Akbas, Zerrin Cebi, Erol Cansiz, Sabri Cemil Isler, Sırmahan Cakarer

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引用次数: 2

Abstract

Purpose: The purpose of this study was to evaluate the efficacy of tranexamic acid (TXA) in reducing blood loss during surgically assisted rapid palatal expansion (SARPE) procedure.

Subjects and methods: A total of 34 patients (12 male, 22 female) who had been treated surgically under general anesthesia with SARPE including pterygoid disjunction for transverse maxillary deficiency (TMD) were included in this study. The study group (n=17) received intravenous (IV) TXA 10 mg/kg as a preoperative bolus; the control group (n=17) received normal saline solution. Preoperative and postoperative haemoglobin and haematocrit values, intraoperative blood loss, and any blood product transfusion were recorded.

Results: Blood loss during SARPE was statistically significantly less in the study group than the control group (p=0.0001).

Conclusion: Preoperative IV administration of TXA can effectively control blood loss during when SARPE with pterygoid disjunction is performed.

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静脉注射氨甲环酸能减少手术辅助下快速腭扩张时的失血吗?

目的:本研究的目的是评估氨甲环酸(TXA)在外科辅助快速腭扩张(SARPE)手术中减少失血的疗效。对象和方法:本研究共纳入34例全麻下经SARPE(包括翼状分离)手术治疗的上颌横向缺陷(TMD)患者，其中男12例，女22例。研究组(n=17)术前给予静脉注射(IV) TXA 10mg /kg;对照组(n=17)给予生理盐水治疗。记录术前和术后血红蛋白和红细胞压积值、术中出血量和任何血制品输血。结果:研究组SARPE失血量明显少于对照组(p=0.0001)。结论:术前静脉给予TXA可有效控制翼状动脉分离SARPE术中出血量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Istanbul University Faculty of Dentistry

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12 weeks