Surgical Management of Recurrent Intracranial Gliomas.

Q2 Medicine Progress in neurological surgery Pub Date : 2018-01-01 Epub Date: 2017-12-14 DOI:10.1159/000464438
Sherise D Ferguson, Eric N Momin, Jeffrey S Weinberg
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引用次数: 3

Abstract

In cases of recurrent gliomas, the treatment options are limited and not yet standardized. Choices usually include re-operation, systemic chemotherapy, salvage re-irradiation, and supportive care, which can be used either separately or in combination. From a surgical perspective, management of recurrent brain tumor poses a significant challenge, as the desire to attain aggressive lesion resection must be balanced against the need to preserve neurological functions and to maximize the quality of life. Additionally, specific practical difficulties in performing repeat craniotomies and significant risk of perioperative morbidity in such cases necessitate careful selection of the optimal candidates for surgery.

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复发性颅内胶质瘤的外科治疗。
在复发性胶质瘤的病例中,治疗选择是有限的,而且尚未标准化。选择通常包括再手术、全身化疗、补救性再照射和支持治疗,可单独使用,也可联合使用。从外科的角度来看,复发性脑肿瘤的治疗提出了一个重大的挑战,因为实现积极切除病灶的愿望必须与保留神经功能和最大限度地提高生活质量的需要相平衡。此外,在这种情况下,重复开颅手术的具体实际困难和围手术期发病率的显著风险需要仔细选择最佳手术候选者。
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期刊介绍: Published since 1966, this series has become universally recognized as the most significant group of books serving neurological surgeons. Volumes feature contributions from distinguished international surgeons, who brilliantly review the literature from the perspective of their own personal experience. The result is a series of works providing critical distillations of developments of central importance to the theory and practice of neurological surgery.
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