Endocarditis due to Rhodotorula mucilaginosa in a kidney transplanted patient: case report and review of medical literature.

JMM case reports Pub Date : 2017-11-02 eCollection Date: 2017-11-01 DOI:10.1099/jmmcr.0.005119
Andrea Maria Cabral, Suzimar da Siveira Rioja, Fabio Brito-Santos, Juliana Ribeiro Peres da Silva, Maria Luíza MacDowell, Marcia S C Melhem, Ana Luíza Mattos-Guaraldi, Raphael Hirata Junior, Paulo Vieira Damasco
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Abstract

Introduction. Endocarditis caused by yeasts is currently an emerging cause of infective endocarditis and, when accompanied byfever of unknown origin, is more severe since interferes with proper diagnosis and endocarditis treatment. Case presentation. The Rio de Janeiro Infective Endocarditis Study Group reports a case of infectious endocarditis (IE) with negative blood cultures in a 45-year-old white female resident in Rio de Janeiro, Brazil, previously submitted to kidney transplantation. After diagnosis and intervention, the valve culture revealed Rhodotorula mucilaginosa. The clinical aspects and overview of endocarditis caused by Rhodotorula spp. demonstrated that R. muscilaginosa have been isolated from the last IE cases from kidney transplanted patients. Conclusion. Though most of the patients (in literature) recovered well from endocarditis caused by Rhodotorula spp., physicians must be aware for diagnosis of fungemia and fungal treatment in kidney transplanted patients suffering of fever of unknown origin in the modern immunosuppressive treatment.

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一名肾移植患者因粘液性红斑癣菌引发的心内膜炎:病例报告和医学文献综述。
导言。酵母菌引起的心内膜炎是目前感染性心内膜炎的一个新病因,如果伴有不明原因的发热,情况会更加严重,因为会影响正确诊断和心内膜炎的治疗。病例介绍。里约热内卢感染性心内膜炎研究小组报告了一例感染性心内膜炎(IE)病例,患者是一名居住在巴西里约热内卢的 45 岁白人女性,血液培养呈阴性。经过诊断和干预,瓣膜培养发现了粘液瘤病毒。罗氏癣菌引起的心内膜炎的临床表现和概况表明,在肾移植患者的最后一例 IE 病例中分离出了粘膜罗氏癣菌。结论虽然(文献中的)大多数患者都从罗氏癣菌引起的心内膜炎中恢复良好,但在现代免疫抑制治疗中,医生必须注意肾移植患者不明原因发热时的真菌血症诊断和真菌治疗。
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