Toxicity of engineered nanomaterials mediated by nano-bio-eco interactions.

Q2 Biochemistry, Genetics and Molecular Biology Journal of Environmental Science and Health Part C-Environmental Carcinogenesis & Ecotoxicology Reviews Pub Date : 2018-01-02 Epub Date: 2018-01-03 DOI:10.1080/10590501.2017.1418793
Xiaojia He, Peter Fu, Winfred G Aker, Huey-Min Hwang
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引用次数: 50

Abstract

Engineered nanomaterials may adversely impact human health and environmental safety by nano-bio-eco interactions not fully understood. Their interaction with biotic and abiotic environments are varied and complicated, ranging from individual species to entire ecosystems. Their behavior, transport, fate, and toxicological profiles in these interactions, addressed in a pioneering study, are subsequently seldom reported. Biological, chemical, and physical dimension properties, the so-called multidimensional characterization, determine interactions. Intermediate species generated in the dynamic process of nanomaterial transformation increase the complexity of assessing nanotoxicity. We review recent progress in understanding these interactions, discuss the challenges of the study, and suggest future research directions.

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纳米-生物-生态相互作用介导的工程纳米材料的毒性。
工程纳米材料可能通过纳米-生物-生态相互作用对人类健康和环境安全产生不利影响。它们与生物和非生物环境的相互作用是多样而复杂的,从单个物种到整个生态系统。它们在这些相互作用中的行为、运输、命运和毒理学特征,在一项开创性的研究中得到了解决,随后很少被报道。生物、化学和物理维度特性,即所谓的多维表征,决定了相互作用。纳米材料在动态转化过程中产生的中间物质增加了纳米毒性评估的复杂性。我们回顾了了解这些相互作用的最新进展,讨论了研究的挑战,并提出了未来的研究方向。
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来源期刊
CiteScore
6.20
自引率
0.00%
发文量
0
审稿时长
>24 weeks
期刊介绍: Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews aims at rapid publication of reviews on important subjects in various areas of environmental toxicology, health and carcinogenesis. Among the subjects covered are risk assessments of chemicals including nanomaterials and physical agents of environmental significance, harmful organisms found in the environment and toxic agents they produce, and food and drugs as environmental factors. It includes basic research, methodology, host susceptibility, mechanistic studies, theoretical modeling, environmental and geotechnical engineering, and environmental protection. Submission to this journal is primarily on an invitational basis. All submissions should be made through the Editorial Manager site, and are subject to peer review by independent, anonymous expert referees. Please review the instructions for authors for manuscript submission guidance.
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