[Myocardial infarction in the course of digoxin and theophylline poisoning].

Przeglad lekarski Pub Date : 2016-01-01
Kamil Zaleski, Agnieszka Górska, Malgorzata Kołodziej, Agnieszka Witkowska, Anna Kujawa, Zuzanna Przykaza, Jaroslaw Szponar
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Abstract

The aim of this paper is to present a case of the patient who was hospitalized in the Toxicology and Cardiology Department because of suicidal digoxin and theophylline intoxication. Both drugs have complicated mechanism of action and affect cardiovascular system differently, but both predispose to ventricular and supraventricular arrhythmias. In the presented patient conduction disorders, cardiac muscle repolarization disorders and ventricular arrhythmias typical to digoxin poisoning were observed. During hospitalization the patient experienced the ECG and biochemical abnormalities resulting from myocardial infarction. In our paper we have analyzed digoxin and theophylline mechanisms of action and possible impact of each of these drugs on the clinical symptoms that our patient presented.

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【地高辛和茶碱中毒过程中的心肌梗死】。
本文的目的是报告一例因地高辛和茶碱中毒自杀而在毒理学和心脏科住院的患者。两种药物作用机制复杂,对心血管系统的影响不同,但均易发生室性心律失常和室上性心律失常。本例患者出现地高辛中毒典型的传导障碍、心肌极化障碍和室性心律失常。住院期间,患者出现心梗所致的心电图及生化异常。在我们的论文中,我们分析了地高辛和茶碱的作用机制,以及这些药物对患者临床症状的可能影响。
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