[Evaluation of chemical compounds acute poisoning risk among Kraków inhabitants in 1966, 1983 and 2015].

Przeglad lekarski Pub Date : 2016-01-01
Janusz Pach, Piotr Hydzik, Malgorzata Kłys, Beata Szkolnicka, Ewelina Paż
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Abstract

The total number of out-patients and hospitalized poisoned patients above 14 years old in Krakow in 1966 was 520 and 2132 in 1983. The incidence of poisoning per 10 000 of Kraków population in 1966 was 25.0 and increased to 36.2 in 1983. The mortality in 1966 was 0.75%. It was low also in 1983 – 1.01%, whatever reached 7.8% if forensic data were included (the fatalities on the spot). There were 847 poisoned patient hospitalized in Clinic of Toxicology UJ CM in 2015 and mortality in this group was 1.06%. Forensic analysis shown decreasing number of deaths on the spot (154 in 1983 and 89 in 2015). The percentage of poisoned with ethanol was declining (78.9% in 1983 and 57.3% in 2015). The frequency of patients treated in intensive care unit were increased from 6% in 1966 to 21.7% in 2015. The percentage of addicted acute intoxicated patients was lower (8%) in 1983 and achieved 21.7% in 2015. Poisoning structure, particularly pharmaceuticals, significantly influenced medical procedures performed in intensive care unit, especially administration of antidotes (5% in 1966 and 48.9% in 2015). Social evolution and changes of culture habits increased percentage of addiction but the number of deaths caused by ethanol on the spot was smaller.

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[1966年、1983年和2015年Kraków居民化合物急性中毒风险评价]。
克拉科夫14岁以上的门诊和住院中毒患者,1966年为520人,1983年为2132人。1966年每10000 ofKraków人口的中毒发生率为25.0,1983年上升到36.2。1966年死亡率为0.75%。这一数字在1983年也很低,为1.01%,如果加上法医数据(现场死亡人数),则达到7.8%。2015年我院毒理学门诊住院中毒患者847例,病死率1.06%。法医分析显示,现场死亡人数正在减少(1983年为154人,2015年为89人)。乙醇中毒比例呈下降趋势(1983年为78.9%,2015年为57.3%)。重症监护病房患者就诊频率由1966年的6%上升至2015年的21.7%。急性中毒成瘾患者比例较1983年(8%)低,2015年达到21.7%。中毒结构,特别是药物,显著影响重症监护病房的医疗程序,特别是解毒剂的使用(1966年为5%,2015年为48.9%)。社会进化和文化习惯的改变增加了酒精成瘾的比例,但酒精导致的当场死亡人数较少。
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