[Advances in host-microbe metabolic axis].

微生物学报 Pub Date : 2017-02-04
Yan Pi, Kan Gao, Weiyun Zhu
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引用次数: 0

Abstract

There are large number of complex and diverse microbiota in gastrointestinal tract, and the gut microbes play an important role in maintaining gut environment homeostasis, not only affecting nutrient absorption and energy metabolism, but also regulating host physiological functions. Intestinal microorganisms can use nutrients of the host and then produce microbial metabolites, finally form host-microbe metabolic axis between host and gut microbes. The axis plays an important role in animal nutrition metabolism and immune homeostasis, and eventually affects the overall metabolism of host. We reviewed the concept of host-microbe metabolic axis, gut-liver axis, gut-brain axis, the interaction between gut microbiota and the host intestinal metabolism axis, and its impact on host health, with the aim to deepen our understanding about the contribution of intestinal microbes to host metabolism.

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宿主-微生物代谢轴研究进展
胃肠道中存在大量复杂多样的微生物群,肠道微生物在维持肠道环境稳态中起着重要作用,不仅影响营养物质的吸收和能量代谢,还调节宿主的生理功能。肠道微生物可以利用宿主的营养物质产生微生物代谢物,最终在宿主和肠道微生物之间形成宿主-微生物代谢轴。该轴在动物营养代谢和免疫稳态中起重要作用,并最终影响宿主的整体代谢。本文综述了宿主-微生物代谢轴、肠-肝轴、肠-脑轴的概念,以及肠道菌群与宿主肠道代谢轴的相互作用及其对宿主健康的影响,旨在加深我们对肠道微生物对宿主代谢的贡献的认识。
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来源期刊
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7960
期刊介绍: Acta Microbiologica Sinica(AMS) is a peer-reviewed monthly (one volume per year)international journal,founded in 1953.It covers a wide range of topics in the areas of general and applied microbiology.The journal publishes original papers,reviews in microbiological science,and short communications describing unusual observations. Acta Microbiologica Sinica has been indexed in Index Copernicus (IC),Chemical Abstract (CA),Excerpt Medica Database (EMBASE),AJ of Viniti (Russia),Biological Abstracts (BA),Chinese Science Citation Database (CSCD),China National Knowledge Infrastructure(CNKI),Institute of Scientific and Technical Information of China(ISTIC),Chinese Journal Citation Report(CJCR),Chinese Biological Abstracts,Chinese Pharmaceutical Abstracts,Chinese Medical Abstracts and Chinese Science Abstracts.
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