[Endogenous production and physiological functions of hydrogen sulfide in facultative anaerobic bacteria].

微生物学报 Pub Date : 2017-02-04
Genfu Wu, Haichun Gao
{"title":"[Endogenous production and physiological functions of hydrogen sulfide in facultative anaerobic bacteria].","authors":"Genfu Wu,&nbsp;Haichun Gao","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>H2S is the third gaseous signaling molecule next to nitric oxide and carbon monoxide, but studies on its physiological functions in bacteria are just emerging. In this paper, we review recent findings regarding endogenous production and physiological functions of H2S in facultative anaerobic bacteria, partly based on our own research on Shewanella oneidensis. There are two principal H2S producing pathways in S. oneidensis:one is through cysteine degradation, and the other is via inorganic sulfur respiration. Endogenous H2S could either benefit mutual growing bacteria by supplying energy and inorganic, or inhibit competing bacteria. Our review attaches particular importance to the role of H2S in bacterial oxidative stress response. On one hand, H2S is able to directly inhibit heme-containing catalase, enhancing killing by H2O2. On the other hand, H2S could activate oxidative response as a signaling molecule, leading to cell protection from the oxidative stress due to elevated expression of H2O2 scavenging and repairing systems. Intriguingly, the dominance of either role is determined by H2S-treating time, that is, inhibition is the immediate response whereas activation of oxidative stress response needs extended treatment. The elucidation of endogenous production and its physiological function of H2S in facultative anaerobic bacteria would improve understanding of biogeochemical sulfur recycling, and facilitate control of infectious bacterial pathogens.</p>","PeriodicalId":7120,"journal":{"name":"微生物学报","volume":"57 2","pages":"170-8"},"PeriodicalIF":0.0000,"publicationDate":"2017-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"微生物学报","FirstCategoryId":"1089","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

H2S is the third gaseous signaling molecule next to nitric oxide and carbon monoxide, but studies on its physiological functions in bacteria are just emerging. In this paper, we review recent findings regarding endogenous production and physiological functions of H2S in facultative anaerobic bacteria, partly based on our own research on Shewanella oneidensis. There are two principal H2S producing pathways in S. oneidensis:one is through cysteine degradation, and the other is via inorganic sulfur respiration. Endogenous H2S could either benefit mutual growing bacteria by supplying energy and inorganic, or inhibit competing bacteria. Our review attaches particular importance to the role of H2S in bacterial oxidative stress response. On one hand, H2S is able to directly inhibit heme-containing catalase, enhancing killing by H2O2. On the other hand, H2S could activate oxidative response as a signaling molecule, leading to cell protection from the oxidative stress due to elevated expression of H2O2 scavenging and repairing systems. Intriguingly, the dominance of either role is determined by H2S-treating time, that is, inhibition is the immediate response whereas activation of oxidative stress response needs extended treatment. The elucidation of endogenous production and its physiological function of H2S in facultative anaerobic bacteria would improve understanding of biogeochemical sulfur recycling, and facilitate control of infectious bacterial pathogens.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
[兼性厌氧细菌中硫化氢的内源性产生和生理功能]。
H2S是仅次于一氧化氮和一氧化碳的第三种气体信号分子,但对其在细菌中的生理功能的研究才刚刚开始。本文综述了兼性厌氧细菌中H2S的内源性产生和生理功能的最新研究成果,部分基于我们对同一希瓦氏菌的研究。水草产生H2S的途径主要有两种:一种是通过半胱氨酸降解,另一种是通过无机硫呼吸。内源性H2S可以通过提供能量和无机物使共生细菌受益,也可以抑制竞争细菌。我们的综述特别重视H2S在细菌氧化应激反应中的作用。一方面,H2S能够直接抑制含血红素过氧化氢酶,增强H2O2对过氧化氢酶的杀伤作用。另一方面,H2S可以作为一种信号分子激活氧化反应,通过提高H2O2清除和修复系统的表达,使细胞免受氧化应激的影响。有趣的是,这两种作用的优势是由h2s处理时间决定的,也就是说,抑制是即时反应,而氧化应激反应的激活需要长期处理。阐明兼性厌氧细菌中H2S的内源产生及其生理功能,有助于加深对硫的生物地球化学循环的认识,有助于感染性细菌病原体的控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
7960
期刊介绍: Acta Microbiologica Sinica(AMS) is a peer-reviewed monthly (one volume per year)international journal,founded in 1953.It covers a wide range of topics in the areas of general and applied microbiology.The journal publishes original papers,reviews in microbiological science,and short communications describing unusual observations. Acta Microbiologica Sinica has been indexed in Index Copernicus (IC),Chemical Abstract (CA),Excerpt Medica Database (EMBASE),AJ of Viniti (Russia),Biological Abstracts (BA),Chinese Science Citation Database (CSCD),China National Knowledge Infrastructure(CNKI),Institute of Scientific and Technical Information of China(ISTIC),Chinese Journal Citation Report(CJCR),Chinese Biological Abstracts,Chinese Pharmaceutical Abstracts,Chinese Medical Abstracts and Chinese Science Abstracts.
期刊最新文献
粪便微生物宏基因组来源L-天冬酰胺酶的性质表征及应用研究 烟草化感自毒物质降解复合菌剂的优化及应用效果评价 花生根际促生复合菌剂对连作花生生理生化指标和根际细菌群落的影响 驯化噬菌体提高噬菌体对碳青霉烯类耐药肺炎克雷伯菌的杀菌能力 植物乳杆菌源胺氧化酶的异源表达及功能结构分析
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1