Role of Nanotechnology in Cosmeceuticals: A Review of Recent Advances.

Journal of Pharmaceutics Pub Date : 2018-03-27 eCollection Date: 2018-01-01 DOI:10.1155/2018/3420204
Shreya Kaul, Neha Gulati, Deepali Verma, Siddhartha Mukherjee, Upendra Nagaich
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Abstract

Nanotechnology manifests the progression in the arena of research and development, by increasing the efficacy of the product through delivery of innovative solutions. To overcome certain drawbacks associated with the traditional products, application of nanotechnology is escalating in the area of cosmeceuticals. Cosmeceuticals are regarded as the fastest growing segment of the personal care industry and the use has risen drastically over the years. Nanocosmeceuticals used for skin, hair, nail, and lip care, for conditions like wrinkles, photoaging, hyperpigmentation, dandruff, and hair damage, have come into widespread use. Novel nanocarriers like liposomes, niosomes, nanoemulsions, microemulsion, solid lipid nanoparticles, nanostructured lipid carrier, and nanospheres have replaced the usage of conventional delivery system. These novel nanocarriers have advantages of enhanced skin penetration, controlled and sustained drug release, higher stability, site specific targeting, and high entrapment efficiency. However, nanotoxicological researches have indicated concern regarding the impact of increased use of nanoparticles in cosmeceuticals as there are possibilities of nanoparticles to penetrate through skin and cause health hazards. This review on nanotechnology used in cosmeceuticals highlights the various novel carriers used for the delivery of cosmeceuticals, their positive and negative aspects, marketed formulations, toxicity, and regulations of nanocosmeceuticals.

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纳米技术在化妆品中的作用:最新进展综述。
纳米技术通过提供创新解决方案提高产品功效,体现了研发领域的进步。为了克服传统产品的某些弊端,纳米技术在药妆领域的应用正在不断升级。药用化妆品被认为是个人护理行业中增长最快的领域,其使用量近年来急剧上升。用于皮肤、头发、指甲和唇部护理,治疗皱纹、光老化、色素沉着、头皮屑和头发损伤等疾病的纳米药剂已开始广泛使用。新型纳米载体,如脂质体、niosomes、纳米乳液、微乳液、固体脂质纳米颗粒、纳米结构脂质载体和纳米球已取代了传统的给药系统。这些新型纳米载体具有增强皮肤渗透性、可控和持续释药、更高的稳定性、特定部位靶向性和高夹持效率等优点。然而,纳米毒理学研究表明,在药用化妆品中越来越多地使用纳米粒子会产生影响,因为纳米粒子有可能穿透皮肤,对健康造成危害。本综述介绍了用于药妆的纳米技术,重点介绍了用于药妆传输的各种新型载体、其积极和消极方面、上市配方、毒性和纳米药妆法规。
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Journal of Pharmaceutics
Journal of Pharmaceutics PHARMACOLOGY & PHARMACY-
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