Polypharmacy in Assisted Living and Impact on Clinical Outcomes.

Barbara Resnick, Elizabeth Galik, Marie Boltz, Sarah Holmes, Steven Fix, Erin Vigne, Shijun Zhu, Regina Lewis
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Abstract

Objective: The purpose of this study was to describe medication use and polypharmacy in assisted living settings. We hypothesized that: 1) age, gender, race, setting, multi-morbidity, and cognitive status would influence polypharmacy; and 2) polypharmacy would be associated with falls, emergency room visits, and hospitalizations.

Design: This was a descriptive study using data from a larger study testing the Dissemination and Implementation of Function Focused Care for Assisted Living (FFC-AL-EIT).

Setting: Participants were recruited from 26 assisted living settings.

Participants: A total of 242 individuals for cohort 1 consented and completed baseline data collection.

Interventions: Data were obtained from participant medical records, observations, and input from staff.

Main outcome measure(s): Age, gender, race, ethnicity, comorbidities, cognitive status, medications, falls, emergency room visits, hospitalizations, function based on the Barthel Index and physical activity using the MotionWatch 8.

Results: Participants had a mean age of 86.86 (standard deviation [SD] = 7.0), the majority were women (n = 179, 74%) and white (n = 233, 96%), with five (SD = 2) diagnoses. The mean number of drugs was seven (SD = 3.56), and 51% were exposed to polypharmacy. The mean Barthel Index score was 63.06 (SD = 20.20), and they engaged in 111,353 (SD = 87,262) counts of activity daily. Fifty-eight residents fell at least once (24%), 22 were sent to the hospital (9%), and 32 (13%) to the emergency room. Neither hypothesis was supported.

Conclusion: Continued research is needed to explore the factors that influence polypharmacy. Identification of these factors will help guide deprescribing so that medication management does not harm older adults physically or cause unnecessary financial burden.

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辅助生活中的多重用药及其对临床结果的影响。
研究目的本研究旨在描述辅助生活环境中的药物使用和多重用药情况。我们假设1)年龄、性别、种族、环境、多病症和认知状况会影响多重用药;以及 2)多重用药与跌倒、急诊就诊和住院有关:本研究是一项描述性研究,使用的数据来自于一项大型研究,该研究测试了 "辅助生活功能集中护理(FFC-AL-EIT)的传播与实施":从 26 个生活辅助设施中招募参与者:第一组共有 242 人同意并完成了基线数据收集:数据来自参与者的医疗记录、观察结果和工作人员的意见:年龄、性别、种族、民族、合并症、认知状况、用药、跌倒、急诊就诊、住院、基于巴特尔指数的功能以及使用 MotionWatch 8 进行的体力活动:参与者的平均年龄为 86.86 岁(标准差 [SD] = 7.0),大多数为女性(n = 179,74%)和白人(n = 233,96%),有 5 项诊断(SD = 2)。平均用药次数为 7 次(SD = 3.56),51% 的患者使用多种药物。他们的巴特尔指数平均分为 63.06 分(标准差 = 20.20),每天的活动量为 111,353 次(标准差 = 87,262 次)。58名住院患者至少摔倒过一次(24%),22人被送往医院(9%),32人(13%)被送往急诊室。两个假设都不成立:需要继续开展研究,探索影响多药治疗的因素。确定这些因素将有助于指导处方的开具,从而避免药物管理对老年人的身体造成伤害或造成不必要的经济负担。
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来源期刊
CONSULTANT PHARMACIST
CONSULTANT PHARMACIST PHARMACOLOGY & PHARMACY-
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期刊介绍: Vision ... The Society"s long-term desire, aspiration, and core purpose. The vision of the American Society of Consultant Pharmacists is optimal medication management and improved health outcomes for all older persons. Mission ... The Society"s strategic position, focus, and reason for being. The American Society of Consultant Pharmacists empowers pharmacists to enhance quality of care for all older persons through the appropriate use of medication and the promotion of healthy aging.
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