THE INCIDENCE OF COLORECTAL CANCER IN KAZAKHSTAN.

M N Turbekova, V L Reznik, I L Menshikova, V B Kamkhen
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Abstract

The purpose of the study is to examine the situation and to ascertain the features of incidence and mortality of colorectal cancer (CRC) in Kazakhstan in 2004-2013 and to give a forecast until 2020.

Materials and methods: The data of new cases and deaths, which are available in the Cancer Registry of Research Institute of Oncology and Radiology of the Republic of Kazakhstan, were applied. in the analyzes the modern methods of variation statistics were applied to determine the average relative number, the study of time series, standard errors of means and other indicators.

Results: The average 10-year CRR incidence was 15.5?0.31 cases per 100 000 population, and the rate of increase reached 2.04% per year where higher rates (+2.28%) were typical for colon cancer. Age is one of the most important factors in the development of CRC. In 30-39 years, the incidence rate increased 11.5 times relative to the age grouping up to 30 years, in 50-59 and 60-69 years, the incidence increases 3.2 and 2.5 times respectively, relative to the previous level. In the group older than 70 years the incidence is 121.1?4.04. On the average during the study period the CRR incidence among females is 1.2 times higher than among males.

Conclusion: The high correlation of developing CRC by age and sex was determined. The death rate from CRC was 9.6?0.25 cases per 100 000. According to the forecast for 2020 the CRC incidence will increase by 11%, and the mortality will not significantly change.

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哈萨克斯坦结直肠癌的发病率。
该研究的目的是检查2004-2013年哈萨克斯坦结直肠癌(CRC)发病率和死亡率的情况并确定其特征,并给出到2020年的预测。材料和方法:采用了哈萨克斯坦共和国肿瘤和放射研究所癌症登记处提供的新病例和死亡数据。在分析中,运用现代变异统计方法确定平均相对数、研究时间序列、均值标准误差等指标。结果:10年CRR平均发病率为15.5 ~ 0.31例/ 10万人,年增长率为2.04%,其中以结肠癌较高(+2.28%)。年龄是影响结直肠癌发展的重要因素之一。30 ~ 39岁年龄组发病率相对于30岁以下年龄组增加11.5倍,50 ~ 59岁和60 ~ 69岁年龄组发病率相对于前水平分别增加3.2倍和2.5倍。在70岁以上人群中,发病率为121.1 ~ 4.04。在研究期间,女性的CRR发病率平均是男性的1.2倍。结论:年龄和性别与结直肠癌的发生高度相关。结直肠癌死亡率为每10万人9.6 - 0.25例。据预测,到2020年,中国的CRC发病率将增加11%,死亡率不会有明显变化。
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