{"title":"Virus-free and cured? The “ART” of adherence. Current efficacy of anti-HIV therapy.","authors":"Thomas Herdegen","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The antiretroviral therapy (ART) enables an almost normal life with HIV infection. Does this also hold true for sexual intercourse, i.e. safe sex without condoms? The European PARTNER-study provides evidence for a very low risk of transmission for condomless sex under optimized conditions such as early, adherent and lasting ART (<200 RNA copies/ml) as well as stable partnerships. The risk of transmission is enhanced with non-compliance or shortlasting (< 6 months) ART, increased HIV-1 RNA load and frequent partnerships.</p>","PeriodicalId":18540,"journal":{"name":"Medizinische Monatsschrift fur Pharmazeuten","volume":"40 4","pages":"143-6"},"PeriodicalIF":0.0000,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medizinische Monatsschrift fur Pharmazeuten","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
The antiretroviral therapy (ART) enables an almost normal life with HIV infection. Does this also hold true for sexual intercourse, i.e. safe sex without condoms? The European PARTNER-study provides evidence for a very low risk of transmission for condomless sex under optimized conditions such as early, adherent and lasting ART (<200 RNA copies/ml) as well as stable partnerships. The risk of transmission is enhanced with non-compliance or shortlasting (< 6 months) ART, increased HIV-1 RNA load and frequent partnerships.
期刊介绍：
•Übersichtsbeiträge zum Beispiel zur Anatomie, Physiologie und Pathophysiologie, zur Pharmakologie einer Substanz- oder Indikationsgruppe, zur Behandlung eines Krankheitsbilds •Fallberichte: der klinisch-pharmazeutische Fall •Pharmakologie aktuell: Neue Therapieprinzipien, neue Wirkungsmechanismen, neue Substanzen werden kurz und verständlich vorgestellt •Ernährungsforum: Fundierte Informationen zur Ernährung und zu Diätformen •Fragen aus der Praxis: Experten beantworten Leseranfragen •Editorial: Kommentare zu pharmazeutischen Themen •Nachrichten aus der medizinischen Forschung mit Neuigkeiten zu Diagnostik und Therapie
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