Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy

Nilika S. Singhal , Adam L. Numis , Morgan B. Lee , Edward F. Chang , Joseph E. Sullivan , Kurtis I. Auguste , Vikram R. Rao
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引用次数: 49

Abstract

Responsive neurostimulation for epilepsy involves an implanted device that delivers direct electrical brain stimulation in response to detection of incipient seizures. Responsive neurostimulation is a safe and effective treatment for adults with drug-resistant epilepsy, but although novel treatments are critically needed for younger patients, responsive neurostimulation is currently not approved for children with drug-resistant epilepsy. Here, we report a 16-year-old patient with seizures arising from eloquent cortex, who was successfully treated with responsive neurostimulation. This case highlights the potential utility of this therapy for pediatric patients and underscores the need for larger studies.

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反应性神经刺激治疗小儿耐药癫痫
癫痫的反应性神经刺激包括一种植入式装置,该装置对早期癫痫发作的检测作出直接的脑电刺激。反应性神经刺激是一种安全有效的治疗成人耐药癫痫的方法,但是尽管年轻患者迫切需要新的治疗方法,反应性神经刺激目前尚未被批准用于治疗儿童耐药癫痫。在这里,我们报告一个16岁的患者癫痫发作引起的雄辩皮层,谁是成功的治疗反应性神经刺激。该病例强调了该疗法对儿科患者的潜在效用,并强调了进行更大规模研究的必要性。
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