Neurosurgical treatment of nonconvulsive status epilepticus due to focal cortical dysplasia

Emin Timer , Saeid Charsouei , Nerses Bebek , Betül Baykan , Bilge Bilgiç , Pulat Akın Sabancı , Yavuz Aras , Nail İzgi , Candan Gürses
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引用次数: 2

Abstract

We present a rare case of focal cortical dysplasia (FCD) and nonconvulsive status epilepticus (NCSE) treated successfully with early surgical intervention. Our case is a 9-year-old boy whose seizures, characterized by short episodes of loss of consciousness, appeared at the age of 7, and he showed progressive cognitive decline in the following years. NCSE was diagnosed, and his MRI revealed FCD in the left frontal region which was the same side as his EEG abnormality. Following lesionectomy, his NCSE disappeared and cognitive functions improved. Histopathologic analysis of the resected tissue revealed type-IIB FCD. This case illustrates the importance of early surgery to help restore cognitive functions by eliminating the clinical and electrophysiological features of NCSE.

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局灶性皮质发育不良所致非惊厥性癫痫持续状态的神经外科治疗
我们报告一例罕见的局灶性皮质发育不良(FCD)和非惊厥性癫痫持续状态(NCSE)通过早期手术干预成功治疗。我们的病例是一个9岁的男孩,他的癫痫发作,以短暂的意识丧失为特征,在7岁时出现,他在接下来的几年里表现出进行性认知衰退。诊断为NCSE, MRI示左额区FCD,与脑电图异常同侧。病灶切除后,患者NCSE消失,认知功能改善。切除组织的组织病理学分析显示为iib型FCD。这个病例说明了早期手术通过消除NCSE的临床和电生理特征来帮助恢复认知功能的重要性。
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