[A Retrospective Analysis on 47 Children with Paragonimiasis in Ningbo City].

Hui-qing Xu, Xin-gang Zhang
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Abstract

A retrospective analysis was performed on 47 children diagnosed with paragonimiasis in Ningbo Women and Children’s Hospital from January 2004 to December 2014. The 47 children comprised 32 boys (68.1%) and 15 girls (48.9%), and 24 cases(51.1%) in urban areas and 23 (48.9%) in rural areas (P>0.05). There was a trend of increase in paragonimiasis occurrence in preschoolers since 2010. Forty-three cases had a history of eating raw or wine-preserved crabs and 4 cases had a history of drinking raw stream water. There were 2 cases of paragonimus encephalopathy and one case accompanied by subcutaneous nodules. Thirty-nine cases showed increases in eosinophil number and proportion in peripheral blood, and 29 cases showed increased serum IgE level. Forty-seven cases had negative results for detection of paragonimus eggs in sputum and stool. The dot immuno-gold filtration-assay and ELISA showed a 100% positive rate for paragonimus serum antibody. All the 47 cases were administered with praziquantel after diagnosis, and no adverse effect was reported during the treatment.

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宁波市47例小儿吸虫病回顾性分析
对2004年1月至2014年12月在宁波市妇女儿童医院诊断为肺吸虫病的47例患儿进行回顾性分析。47例儿童中,男孩32例(68.1%),女孩15例(48.9%),城镇24例(51.1%),农村23例(48.9%)(P>0.05)。2010年以来,学龄前儿童吸虫病发病率呈上升趋势。43例有生吃或酒腌渍螃蟹史,4例有饮用未经处理的溪水史。肺吸虫性脑病2例,伴皮下结节1例。39例外周血嗜酸性粒细胞数量及比例升高,29例血清IgE水平升高。47例痰、粪便吸虫卵检出阴性。斑点免疫金滤法和酶联免疫吸附试验显示吸虫血清抗体阳性率为100%。47例患者诊断后均给予吡喹酮治疗,治疗过程中无不良反应报告。
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