Intrinsic and Extrinsic Factors Affecting Skin Surface pH.

Current problems in dermatology Pub Date : 2018-01-01 Epub Date: 2018-08-21 DOI:10.1159/000489516
Miranda A Farage, William Hood, Enzo Berardesca, Howard Maibach
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引用次数: 8

Abstract

The body skin pH can usually vary from 4.0 to 7.0 depending on location. The presence of natural acidic compounds on the skin surface helps maintain the skin's physicochemical properties as well as its protective functions. Since the slightly acidic pH of the skin is extremely important for the skin's protective function, the skin is widely known as "acid mantel." Factors such as age, race, gender, body sites, biochemical differences, and even washing affect the pH of the stratum corneum. Recent clinical studies using an emollient-base finish product using the traditional way of measuring skin pH produced results that indicated an apparent increase in skin pH. The apparent pH increase with these products is most probably an artifact of the skin pH measurement technique. Our findings show that certain petrolatum-based emollients and components could create a protective barrier and help maintain the healthy acidity of the skin. Our work provides new evidence of emollients helping to stabilize skin pH in its natural balanced state rather than affecting it. This new learning should be taken into consideration by other researchers in the area of skin pH as well as in clinical studies to avoid misleading results.

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影响皮肤表面pH值的内在和外在因素。
根据位置的不同,人体皮肤的pH值通常在4.0到7.0之间变化。皮肤表面天然酸性化合物的存在有助于维持皮肤的物理化学特性以及它的保护功能。由于皮肤的微酸性pH值对皮肤的保护功能极为重要,因此皮肤被广泛称为“酸性壁炉”。年龄、种族、性别、身体部位、生化差异,甚至洗涤等因素都会影响角质层的pH值。最近的临床研究使用传统方法测量皮肤pH值的润肤剂成品,结果表明皮肤pH值明显增加。这些产品的明显pH值增加很可能是皮肤pH值测量技术的人工产物。我们的研究结果表明,某些以凡士林为基础的润肤剂和成分可以形成一个保护屏障,帮助保持皮肤的健康酸度。我们的工作提供了新的证据,证明润肤剂有助于将皮肤pH值稳定在自然平衡状态,而不是影响它。这一新发现应该被皮肤pH值领域的其他研究人员以及临床研究人员考虑,以避免误导结果。
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