Assessment of left ventricular regional wall motion abnormalities using regional time-volume curves obtained by real time three-dimensional echocardiography

IF 1.4 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Egyptian Heart Journal Pub Date : 2018-09-01 DOI:10.1016/j.ehj.2018.02.002
Ghada Youssef, Zakarya Saad, Waleed Ammar, Yasser Sharaf
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Abstract

Background

Three-dimensional echocardiography provides a volumetric measurement of global and regional left ventricular (LV) function. It avoids the subjectivity of 2D echocardiography in the assessment of regional wall motion abnormalities (RWMA).

Purpose

Evaluate the feasibility and practicality of 3D echocardiography in the evaluation of ischemic patients with abnormal regional LV contractility.

Methods

The study included 40 patients with ischemic heart disease and RWMA as well as 30 control subjects. They underwent routine clinical examination and conventional 2D echocardiographic assessment. Segments were categorized as; normal, hypokinetic; akinetic or dyskinetic. Three-dimensional echocardiographic images were acquired and later on analyzed offline. Global LV function was semi-automatically calculated by the machine using volumetric measurements. Regional LV function was calculated manually for the 17 LV segments by detecting the end-diastolic (EDD) and end-systolic (ESD) points on the specific segment volume curve and the regional ejection fraction (EF) was calculated by the following formula {(EDDx-ESDx)/EDDx}, where x represents the specific segment. Regional EF was compared between patients and control subjects.

Results

The mean age was 55.0 ± 8.0 and 32.6 ± 8.5 years (P < 0.001) in patients and control groups, respectively. No statistically significant difference in EF between 2D and 3D images (47.3 ± 10.5 vs 48.0 ± 8.0, p = 0.6). There was a good correlation between the 2D-RWMA and 3D-regional EF, and this correlation was consistent in the whole 17 segments.

Conclusion

Three-dimensional echocardiography is an easy, non-invasive and objective tool to detect regional wall motion abnormalities in ischemic patients. It shows comparable results with conventional 2D images with the advantage of quantitative assessment of regional myocardial function.

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利用实时三维超声心动图获得的局部时间-体积曲线评估左室局部壁运动异常
三维超声心动图提供了整体和局部左心室(LV)功能的体积测量。它避免了二维超声心动图在评估区域壁运动异常(RWMA)时的主观性。目的评价三维超声心动图评价局部左室收缩力异常缺血性患者的可行性和实用性。方法选取缺血性心脏病合并RWMA患者40例,对照组30例。进行常规临床检查和常规二维超声心动图评估。分段分类为;正常,运动功能减退的;动态的或不动态的获得三维超声心动图图像,然后离线分析。全局LV函数由机器使用体积测量半自动计算。通过检测特定节段容积曲线上的舒张末期(EDD)和收缩末期(ESD)点,人工计算17个左室节段的区域左室功能,计算区域射血分数(EF),公式为{(EDDx- esdx)/EDDx},其中x代表特定节段。比较患者与对照组的区域EF。结果患者和对照组的平均年龄分别为55.0 ± 8.0岁和32.6 ± 8.5 岁(P < 0.001)。2D和3D影像的EF无统计学差异(47.3 ± 10.5 vs 48.0 ± 8.0,p = 0.6)。2D-RWMA与3D-regional EF具有良好的相关性,且这种相关性在整个17个节段中是一致的。结论三维超声心动图是一种简便、无创、客观的检测局部缺血性心壁运动异常的工具。结果与常规二维图像相当,具有定量评估局部心肌功能的优势。
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来源期刊
Egyptian Heart Journal
Egyptian Heart Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.10
自引率
0.00%
发文量
82
审稿时长
9 weeks
期刊介绍: The Egyptian Heart Journal is the official journal of the Egyptian Society of Cardiology. It is an international journal that publishes peer-reviewed articles on all aspects of cardiovascular disease, including original clinical studies and translational investigations. The journal publishes research, review articles, case reports and commentary articles, as well as editorials interpreting and commenting on the research presented. In addition, it provides a forum for the exchange of information on all aspects of cardiovascular medicine, including educational issues.
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