Malignant melanoma of the small bowel presenting with intussusception in a woman: a case report.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2017-05-01 Epub Date: 2017-05-15 DOI:10.2217/mmt-2016-0028
Abby Vrable, Richard Chang
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引用次数: 6

Abstract

Primary malignant melanoma originating in the small bowel is very rare. We report the case of primary malignant melanoma of the small bowel with secondary intussusception in a 51-year-old female with no prior history of cutaneous melanoma. The patient was admitted to the hospital for clinical bowel obstruction after 6 months of varying symptoms of antecedent syncopal events secondary to profound anemia due to iron deficiency followed later by vomiting, abdominal pain and weight loss. A CT scan showed intussusception and she underwent a small bowel resection. Diagnosis of malignant melanoma was confirmed post-operatively following immunohistochemistry. The patient history and postoperative investigation excluded the existence of a primary lesion elsewhere. Our case represents an aggressive primary small bowel melanoma presenting as intussusception.

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女性小肠恶性黑色素瘤伴肠套叠一例报告。
原发性恶性黑色素瘤起源于小肠是非常罕见的。我们报告一例原发性小肠恶性黑色素瘤伴继发性肠套叠的病例,患者为51岁女性,既往无皮肤黑色素瘤病史。患者因临床肠梗阻入院,6个月后出现各种晕厥症状,继发于缺铁引起的深度贫血,随后出现呕吐、腹痛和体重减轻。CT扫描显示肠套叠,她接受了小肠切除术。术后免疫组化诊断为恶性黑色素瘤。患者病史和术后调查排除了其他地方原发病变的存在。本病例为侵袭性原发性小肠黑色素瘤,表现为肠套叠。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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