{"title":"[COMPARATIVE CHARACTERIZATION OF HYALURONIDASE ISOFORMS OF THE 1ST TYPE IN SOMATIC TISSUES AND SERUM OF WHITE RATS].","authors":"S G Dzgoev","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>There are identified 3 proteins with molecular mass of 63, 73 and 132 kDa, exhibiting the properties of the hyaluronidase of the 1st type in the liver, spleen, renal papilla, skin and serum by the method of zymography. A protein with a molecular mass of 73 kDa was detected in all studied tissues and serum, while protein with a molecular mass of 63 kDa was present only in the tissues, and the protein with molecular mass of 132 kDa was present only in the serum. It is discussed the possibility of aggregation of 63 kDa protein molecules in the dimers with the formation of a 132 kDa protein in the serum.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"102 8","pages":"963-7"},"PeriodicalIF":0.0000,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
There are identified 3 proteins with molecular mass of 63, 73 and 132 kDa, exhibiting the properties of the hyaluronidase of the 1st type in the liver, spleen, renal papilla, skin and serum by the method of zymography. A protein with a molecular mass of 73 kDa was detected in all studied tissues and serum, while protein with a molecular mass of 63 kDa was present only in the tissues, and the protein with molecular mass of 132 kDa was present only in the serum. It is discussed the possibility of aggregation of 63 kDa protein molecules in the dimers with the formation of a 132 kDa protein in the serum.
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