The Association between Earlobe Crease (Frank's Sign) and Abnormal Ankle-Brachial Index Determination Is Related to Age: A Population-Based Study.

IF 2.5 Q2 PERIPHERAL VASCULAR DISEASE International Journal of Vascular Medicine Pub Date : 2018-09-02 eCollection Date: 2018-01-01 DOI:10.1155/2018/4735731
Oscar H Del Brutto, Robertino M Mera, Aldo F Costa, Mauricio Zambrano, Mark J Sedler
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引用次数: 8

Abstract

Background: Information on the association between earlobe crease (ELC) and peripheral artery disease is limited. We assessed this association in community-dwelling older adults.

Study design: A total of 294 Atahualpa residents aged ≥60 years were enrolled. ELC were visually identified by two raters. The ankle-brachial index (ABI), used as a surrogate of peripheral artery disease, was categorized using American Heart Association criteria. Using logistic regression and probability models, adjusted for demographics and cardiovascular risk factors, we assessed the relationship between ELC and abnormal ABI determinations, as well as the influence of age on this association.

Results: ELC was identified in 141 (48%) individuals, and abnormal ABI determination was carried out in 56 (19%). The association between ELC and abnormal ABI was nonsignificant in logistic regression and probability models with individuals stratified according to their median age.

Conclusions: The association between ELC and abnormal ABI determinations is probably attenuated by the high prevalence of both conditions in older persons. ELC might not be useful for identifying candidates for ABI determination.

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耳垂折痕(弗兰克氏征)与异常踝臂指数测定之间的关系与年龄有关:一项基于人群的研究。
背景:关于耳垂皱褶(ELC)与外周动脉疾病之间关系的信息有限。我们在社区居住的老年人中评估了这种关联。研究设计:共纳入294名年龄≥60岁的Atahualpa居民。两名评分员对ELC进行视觉识别。踝肱指数(ABI),作为外周动脉疾病的替代指标,根据美国心脏协会的标准进行分类。使用逻辑回归和概率模型,调整人口统计学和心血管危险因素,我们评估了ELC和异常ABI测定之间的关系,以及年龄对这种关联的影响。结果:141例(48%)检测到ELC, 56例(19%)检测到ABI异常。在逻辑回归和概率模型中,ELC与异常ABI之间的相关性不显著,个体按年龄中位数分层。结论:ELC和异常ABI测定之间的关联可能因老年人中这两种情况的高患病率而减弱。ELC可能不能用于确定ABI测定的候选物。
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来源期刊
International Journal of Vascular Medicine
International Journal of Vascular Medicine PERIPHERAL VASCULAR DISEASE-
CiteScore
3.50
自引率
0.00%
发文量
7
审稿时长
16 weeks
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